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Benjamin Gottschalk

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Articles 53
Citations 823
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Recent Articles
11.
Goeritzer M, Kuentzel K, Beck S, Korbelius M, Rainer S, Bradic I, et al.
Int J Mol Sci . 2023 Feb; 24(4). PMID: 36834530
Monoglyceride lipase (MGL) hydrolyzes monoacylglycerols (MG) to glycerol and one fatty acid. Among the various MG species, MGL also degrades 2-arachidonoylglycerol, the most abundant endocannabinoid and potent activator of the...
12.
Bachkoenig O, Gottschalk B, Malli R, Graier W
Curr Top Membr . 2022 Nov; 90:13-35. PMID: 36368872
Mitochondria actively contribute to cellular Ca homeostasis. The molecular mechanisms of mitochondrial Ca uptake and release are well characterized and are attributed to the multi-protein assembly of the mitochondrial Ca...
13.
Anand U, Shteinfer-Kuzmine A, Sela G, Santhanam M, Gottschalk B, Boujemaa-Paterski R, et al.
Biomolecules . 2022 Oct; 12(10). PMID: 36291596
The mitochondrial voltage-dependent anion channel-1 (VDAC1) protein functions in a variety of mitochondria-linked physiological and pathological processes, including metabolism and cell signaling, as well as in mitochondria-mediated apoptosis. VDAC1 interacts...
14.
Gottschalk B, Koshenov Z, Bachkoenig O, Rost R, Malli R, Graier W
Front Cell Dev Biol . 2022 Sep; 10:918691. PMID: 36158213
Endoplasmic reticulum (ER) functions critically depend on a suitable ATP supply to fuel ER chaperons and protein trafficking. A disruption of the ability of the ER to traffic and fold...
15.
Gottschalk B, Koshenov Z, Waldeck-Weiermair M, Radulovic S, Oflaz F, Hirtl M, et al.
Commun Biol . 2022 Jul; 5(1):649. PMID: 35778442
Mitochondrial ultrastructure represents a pinnacle of form and function, with the inner mitochondrial membrane (IMM) forming isolated pockets of cristae membrane (CM), separated from the inner-boundary membrane (IBM) by cristae...
16.
Klec C, Knutsen E, Schwarzenbacher D, Jonas K, Pasculli B, Heitzer E, et al.
Cell Mol Life Sci . 2022 Jul; 79(7):391. PMID: 35776213
The RNA-binding protein ALYREF (THOC4) is involved in transcriptional regulation and nuclear mRNA export, though its role and molecular mode of action in breast carcinogenesis are completely unknown. Here, we...
17.
Tawfik I, Gottschalk B, Jarc A, Bresilla D, Rost R, Obermayer-Pietsch B, et al.
Free Radic Biol Med . 2022 Jan; 181:197-208. PMID: 35091061
Thyroid hormones act as master regulators of cellular metabolism. Thereby, the biologically active triiodothyronine (T3) induces the expression of genes to enhance mitochondrial metabolic function. Notably, Ca ions are necessary...
18.
Koshenov Z, Oflaz F, Hirtl M, Gottschalk B, Rost R, Malli R, et al.
Commun Biol . 2022 Jan; 5(1):76. PMID: 35058562
In contrast to long-term metabolic reprogramming, metabolic rewiring represents an instant and reversible cellular adaptation to physiological or pathological stress. Ca signals of distinct spatio-temporal patterns control a plethora of...
19.
Gottschalk B, Madreiter-Sokolowski C, Graier W
Cell Calcium . 2021 Dec; 101:102517. PMID: 34915234
OPA1 and MICU1 are both involved in the regulation of mitochondrial Ca uptake and the stabilization of the cristae junction, which separates the inner mitochondrial membrane into the interboundary membrane...
20.
Oflaz F, Koshenov Z, Hirtl M, Rost R, Bachkoenig O, Gottschalk B, et al.
Int J Mol Sci . 2021 Aug; 22(15). PMID: 34360954
Ca-dependent gene regulation controls several functions to determine the fate of the cells. Proteins of the nuclear factor of activated T-cells (NFAT) family are Ca sensitive transcription factors that control...