Benjamin Ducarouge
Overview
Explore the profile of Benjamin Ducarouge including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
305
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0
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Recent Articles
1.
Patte C, Pommier R, Ferrari A, Chung F, Ouzounova M, Moulle P, et al.
Nat Commun
. 2025 Mar;
16(1):2197.
PMID: 40038310
Small intestinal neuroendocrine tumors (siNETs) are rare bowel tumors arising from malignant enteroendocrine cells, which normally regulate digestion throughout the intestine. Though infrequent, their incidence is rising through better diagnosis,...
2.
Pearson J, Huang K, Dela Pena L, Ducarouge B, Mehlen P, Bremner R
Cancer Res Commun
. 2024 Aug;
4(9):2374-2383.
PMID: 39172021
Significance: Netrins are widely perceived as procancer proteins; however, we uncover an anticancer function for Netrin-1 and its receptor UNC5B.
3.
Dudgeon C, Casabianca A, Harris C, Ogier C, Bellina M, Fiore S, et al.
Cell Rep
. 2023 Nov;
42(11):113369.
PMID: 37922311
The biology of metastatic pancreatic ductal adenocarcinoma (PDAC) is distinct from that of the primary tumor due to changes in cell plasticity governed by a distinct transcriptome. Therapeutic strategies that...
4.
Ducarouge B, Redavid A, Victoor C, Chira R, Fonseca A, Hervieu M, et al.
Cell Death Differ
. 2023 Aug;
30(10):2201-2212.
PMID: 37633969
Drug resistance and cancer relapse represent significant therapeutic challenges after chemotherapy or immunotherapy, and a major limiting factor for long-term cancer survival. Netrin-1 was initially identified as a neuronal navigation...
5.
Cassier P, Navaridas R, Bellina M, Rama N, Ducarouge B, Hernandez-Vargas H, et al.
Nature
. 2023 Aug;
620(7973):409-416.
PMID: 37532934
Netrin-1 is upregulated in cancers as a protumoural mechanism. Here we describe netrin-1 upregulation in a majority of human endometrial carcinomas (ECs) and demonstrate that netrin-1 blockade, using an anti-netrin-1...
6.
Lengrand J, Pastushenko I, Vanuytven S, Song Y, Venet D, Sarate R, et al.
Nature
. 2023 Aug;
620(7973):402-408.
PMID: 37532929
Epithelial-to-mesenchymal transition (EMT) regulates tumour initiation, progression, metastasis and resistance to anti-cancer therapy. Although great progress has been made in understanding the role of EMT and its regulatory mechanisms in...
7.
Kryza D, Wischhusen J, Richaud M, Hervieu M, Sidi Boumedine J, Delcros J, et al.
EMBO Mol Med
. 2023 Mar;
15(4):e16732.
PMID: 36876343
Targeted radionuclide therapy is a revolutionary tool for the treatment of highly spread metastatic cancers. Most current approaches rely on the use of vectors to deliver radionuclides to tumor cells,...
8.
Jiang S, Richaud M, Vieugue P, Rama N, Delcros J, Siouda M, et al.
EMBO Mol Med
. 2021 Mar;
13(4):e12878.
PMID: 33719214
The navigation cue netrin-1 is well-documented for its key role in cancer development and represents a promising therapeutic target currently under clinical investigation. Phase 1 and 2 clinical trials are...
9.
Renders S, Svendsen A, Panten J, Rama N, Maryanovich M, Sommerkamp P, et al.
Nat Commun
. 2021 Jan;
12(1):608.
PMID: 33504783
Haematopoietic stem cells (HSCs) are characterized by their self-renewal potential associated to dormancy. Here we identify the cell surface receptor neogenin-1 as specifically expressed in dormant HSCs. Loss of neogenin-1...
10.
Sung P, Rama N, Imbach J, Fiore S, Ducarouge B, Neves D, et al.
Cancer Res
. 2019 May;
79(14):3651-3661.
PMID: 31088838
Netrin-1 is upregulated in a large fraction of human neoplasms. In multiple animal models, interference with netrin-1 is associated with inhibition of tumor growth and metastasis. Although netrin-1 upregulation was...