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Benjamin Drogat

Explore the profile of Benjamin Drogat including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 1069
Followers 0
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Recent Articles
1.
Mauri F, Schepkens C, Lapouge G, Drogat B, Song Y, Pastushenko I, et al.
Nat Cancer . 2022 Feb; 2(11):1152-1169. PMID: 35122061
The nongenetic mechanisms required to sustain malignant tumor state are poorly understood. During the transition from benign tumors to malignant carcinoma, tumor cells need to repress differentiation and acquire invasive...
2.
Nokin M, Darbo E, Travert C, Drogat B, Lacouture A, San Jose S, et al.
JCI Insight . 2020 Aug; 5(15). PMID: 32759499
Platinum-based chemotherapy in combination with immune-checkpoint inhibitors is the current standard of care for patients with advanced lung adenocarcinoma (LUAD). However, tumor progression evolves in most cases. Therefore, predictive biomarkers...
3.
Lucchesi C, Drogat B, Santamaria D, Cousin S, Italiano A
Lung Cancer . 2018 Oct; 126:227-229. PMID: 30342857
No abstract available.
4.
Beck B, Lapouge G, Rorive S, Drogat B, Desaedelaere K, Delafaille S, et al.
Cell Stem Cell . 2015 Jan; 16(1):67-79. PMID: 25575080
Twist1 promotes epithelial-to-mesenchymal transition (EMT), invasion, metastasis, and cancer stem cell (CSC) properties. However, it remains unclear whether Twist1 is also required for tumor initiation and whether Twist1-induced cancer stemness...
5.
Haenebalcke L, Goossens S, Naessens M, Kruse N, Farhang Ghahremani M, Bartunkova S, et al.
Stem Cell Rev Rep . 2013 Jul; 9(6):774-85. PMID: 23877658
The conditional Cre/loxP system and/or the doxycycline (Dox) inducible Tet-on/off system are widely used in mouse transgenesis but often require time consuming, inefficient cloning/screening steps and extensive mouse breeding strategies....
6.
Tondeleir D, Drogat B, Slowicka K, Bakkali K, Bartunkova S, Goossens S, et al.
PLoS One . 2013 Jul; 8(6):e67855. PMID: 23840778
The functions of actin family members during development are poorly understood. To investigate the role of beta-actin in mammalian development, a beta-actin knockout mouse model was used. Homozygous beta-actin knockout...
7.
Mascre G, Dekoninck S, Drogat B, Youssef K, Brohee S, Sotiropoulou P, et al.
Nature . 2012 Sep; 489(7415):257-62. PMID: 22940863
The skin interfollicular epidermis (IFE) is the first barrier against the external environment and its maintenance is critical for survival. Two seemingly opposite theories have been proposed to explain IFE...
8.
Beck B, Driessens G, Goossens S, Youssef K, Kuchnio A, Caauwe A, et al.
Nature . 2011 Oct; 478(7369):399-403. PMID: 22012397
Angiogenesis is critical during tumour initiation and malignant progression. Different strategies aimed at blocking vascular endothelial growth factor (VEGF) and its receptors have been developed to inhibit angiogenesis in cancer...
9.
Goossens S, Janzen V, Bartunkova S, Yokomizo T, Drogat B, Crisan M, et al.
Blood . 2011 Mar; 117(21):5620-30. PMID: 21355089
Zeb2 (Sip1/Zfhx1b) is a member of the zinc-finger E-box-binding (ZEB) family of transcriptional repressors previously demonstrated to regulate epithelial-to-mesenchymal transition (EMT) processes during embryogenesis and tumor progression. We found high...
10.
Drogat B, Kalucka J, Gutierrez L, Hammad H, Goossens S, Farhang Ghahremani M, et al.
Blood . 2010 Jun; 116(12):2141-51. PMID: 20554972
To determine the role of vascular endothelial growth factor (Vegf) in embryonic erythroid development we have deleted or overexpressed Vegf specifically in the erythroid lineage using the EpoR-iCre transgenic line...