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Benedikt Engels

Explore the profile of Benedikt Engels including associated specialties, affiliations and a list of published articles. Areas
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Citations 971
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Recent Articles
1.
Engels B, De Paoli A, Delmastro E, Munoz F, Vagge S, Norkus D, et al.
Cancers (Basel) . 2023 Aug; 15(15). PMID: 37568685
Background: Preoperative chemoradiotherapy (CRT) is the standard treatment for T3-4 rectal cancer. Here, we compared image-guided and intensity-modulated RT (IG-IMRT) with a simultaneous integrated boost (SIB) (instead of concomitant chemotherapy)...
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McElroy C, Engels B, Meusinger R, Jennewein S
Chembiochem . 2023 May; 24(14):e202300179. PMID: 37171879
The melleolides are a family of structurally and functionally diverse sesquiterpenoids with potential applications as fungicides, antimicrobials, and cancer therapeutics. The initial and terminal steps of the biosynthesis pathway in...
3.
AlGhamdi H, Dhont J, Krayem M, De Bruyn P, Engels B, Van Gestel D, et al.
Cancers (Basel) . 2022 Apr; 14(8). PMID: 35454951
Over the last years, the oligometastatic disease state has gained more and more interest, and randomized trials are now suggesting an added value of stereotactic radiotherapy on all macroscopic disease...
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Engels B, Heinig U, McElroy C, Meusinger R, Grothe T, Stadler M, et al.
Appl Microbiol Biotechnol . 2020 Nov; 105(1):211-224. PMID: 33191459
Melleolides and armillyl orsellinates are protoilludene-type aryl esters that are synthesized exclusively by parasitic fungi of the globally distributed genus Armillaria (Agaricomycetes, Physalacriaceae). Several of these compounds show potent antimicrobial...
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Parschat K, Schreiber S, Wartenberg D, Engels B, Jennewein S
ACS Synth Biol . 2020 Sep; 9(10):2784-2796. PMID: 32966739
Human milk oligosaccharides (HMOs) are unique components of human breast milk. Their large-scale production by fermentation allows infant formulas to be fortified with HMOs, but current fermentation processes require lactose...
7.
Dirix P, Strijbos M, Van den Mooter T, Liefhooghe N, Van Bruwaene S, Uvin P, et al.
Future Oncol . 2020 May; 16(16):1083-1189. PMID: 32356465
Apalutamide, a competent inhibitor of the androgen receptor, has shown promising clinical efficacy results for patients with advanced prostate cancer. Here, we describe the rationale and design for the SAVE...
8.
Van den Begin R, Engels B, Collen C, de Vin T, Defauw A, Dubaere E, et al.
Radiother Oncol . 2019 Apr; 133:113-119. PMID: 30935566
Background And Purpose: Stereotactic radiotherapy (SRT, SBRT) is widely used in oligometastatic cancer, but the heterogeneity of the population complicates estimation of the prognosis. We investigated the role of different...
9.
de Mey S, Jiang H, Wang H, Engels B, Gevaert T, Dufait I, et al.
Radiother Oncol . 2018 Jun; 127(3):361-369. PMID: 29871814
The management of locally advanced rectal cancer has passed a long way of developments, where total mesorectal excision and preoperative radiotherapy are crucial to secure clinical outcome. These and other...
10.
Van den Begin R, Kleijnen J, Engels B, Philippens M, van Asselen B, Raaymakers B, et al.
Acta Oncol . 2017 Nov; 57(6):723-727. PMID: 29157069
Purpose: Few data is available on rectal tumor shrinkage during preoperative chemoradiotherapy (CRT). This regression pattern is interesting to optimize timing of dose escalation on the tumor. Methods: Gross tumor...