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Benedictor Alexander Nguchu

Explore the profile of Benedictor Alexander Nguchu including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 147
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Recent Articles
1.
Nguchu B, Han Y, Wang Y, Shaw P
Front Psychiatry . 2025 Feb; 16:1453852. PMID: 40018689
Introduction: Parkinson's disease () heterogeneity poses challenges to the current development of discovering the best therapeutic targets. Methods: Here, we employ K-means and hierarchical clustering algorithms on data from the...
2.
Wang Y, Wang H, Hu S, Nguchu B, Zhang D, Chen S, et al.
Hum Brain Mapp . 2024 Aug; 45(11):e26800. PMID: 39093044
White matter (WM) functional activity has been reliably detected through functional magnetic resonance imaging (fMRI). Previous studies have primarily examined WM bundles as unified entities, thereby obscuring the functional heterogeneity...
3.
Hu S, Wei T, Li C, Wang X, Nguchu B, Wang Y, et al.
Neuroimage Clin . 2024 Jun; 43:103618. PMID: 38830274
Extensive neuroimaging abnormalities in subcortical regions build the pathophysiological basis of Wilson's disease (WD). Yet, subcortical topographic organization fails to articulate, leaving a huge gap in understanding the neural mechanism...
4.
Lu Q, Chen J, Wang Y, Huang L, Jiang Z, Nguchu B, et al.
Psychiatry Investig . 2023 Apr; 20(4):334-340. PMID: 37098660
Objective: This study uses structural magnetic resonance imaging to explore changes in the cerebellar lobules in patients with autism spectrum disorder (ASD) and further analyze the correlation between cerebellar structural...
5.
Liu J, Nguchu B, Liu D, Qi Y, Aili X, Han S, et al.
Front Immunol . 2023 Jan; 13:1067795. PMID: 36713432
Objective: To use SIV-mac239-infected Chinese rhesus monkeys to study white matter changes with and without regular combined antiretroviral therapy (cART) and the relationships between the changes and clinical results. Methods:...
6.
de Dieu Uwisengeyimana J, Wang Y, Nguchu B, Wang X, Qiu B
J Neurol Sci . 2022 Oct; 442:120435. PMID: 36201963
Introduction: While several studies have substantially revealed the influence of the apolipoprotein E4 genotype (APOE4) on the vulnerability of Alzheimer's disease (AD), there are still far fewer studies investigating whether...
7.
Xu J, Su Y, Fu J, Wang X, Nguchu B, Qiu B, et al.
Eur J Neurol . 2022 Jun; 29(10):2895-2904. PMID: 35712978
Background And Purpose: Cerebral amyloid angiopathy (CAA) is characterized by β-amyloid deposition in cortical and leptomeningeal arterioles, which might result from glymphatic dysfunction. The aim was to explore glymphatic function...
8.
Nguchu B, Zhao J, Wang Y, de Dieu Uwisengeyimana J, Wang X, Qiu B, et al.
Front Neurol . 2022 Apr; 13:819594. PMID: 35359662
Objective: The brain relies on the glymphatic system to clear metabolic wastes and maintain brain homeostasis to fulfill its functions better. Yet, the complexity of the glymphatic flow and clearance...
9.
de Dieu Uwisengeyimana J, Nguchu B, Wang Y, Zhang D, Liu Y, Jiang Z, et al.
Aging Clin Exp Res . 2022 Jan; 34(6):1303-1313. PMID: 35023051
Background: Intervention against age-related neurodegenerative diseases may be difficult once extensive structural and functional deteriorations have already occurred in the brain. Aim: Investigating 6-year longitudinal changes and implications of regional...
10.
Komolafe T, Cao Y, Nguchu B, Monkam P, Olaniyi E, Sun H, et al.
Acad Radiol . 2021 Oct; 28(11):1507-1523. PMID: 34649779
Rationale And Objective: To perform a meta-analysis to compare the diagnostic test accuracy (DTA) of deep learning (DL) in detecting coronavirus disease 2019 (COVID-19), and to investigate how network architecture...