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Ben J Nichols

Explore the profile of Ben J Nichols including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 242
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Recent Articles
1.
Ficht X, Ruef N, Stolp B, Samson G, Moalli F, Page N, et al.
J Immunol . 2019 Sep; 203(9):2377-2387. PMID: 31548330
Flotillin-1 (Flot1) is an evolutionary conserved, ubiquitously expressed lipid raft-associated scaffolding protein. Migration of Flot1-deficient neutrophils is impaired because of a decrease in myosin II-mediated contractility. Flot1 also accumulates in...
2.
Lee T, McKleroy W, Khalifeh-Soltani A, Sakuma S, Lazarev S, Riento K, et al.
Mol Biol Cell . 2014 Jan; 25(5):583-93. PMID: 24403604
Tissue fibrosis occurs when matrix production outpaces matrix degradation. Degradation of collagen, the main component of fibrotic tissue, is mediated through an extracellular proteolytic pathway and intracellular pathway of cellular...
3.
Ludwig A, Otto G, Riento K, Hams E, Fallon P, Nichols B
J Cell Biol . 2010 Nov; 191(4):771-81. PMID: 21059848
We studied the function of plasma membrane microdomains defined by the proteins flotillin 1 and flotillin 2 in uropod formation and neutrophil chemotaxis. Flotillins become concentrated in the uropod of...
4.
Hansen C, Nichols B
Trends Cell Biol . 2010 Feb; 20(4):177-86. PMID: 20153650
Caveolae are ampullate (flask-shaped) invaginations that are abundant in the plasma membrane of many mammalian cell types. Although caveolae are implicated in a wide range of processes including endothelial transcytosis,...