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Belinda Baquero-Perez

Explore the profile of Belinda Baquero-Perez including associated specialties, affiliations and a list of published articles. Areas
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Citations 309
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Recent Articles
1.
Baquero-Perez B, Bortoletto E, Rosani U, Delgado-Tejedor A, Medina R, Novoa E, et al.
Viruses . 2024 Jun; 16(6). PMID: 38932237
The genomes of positive-sense (+) single-stranded RNA (ssRNA) viruses are believed to be subjected to a wide range of RNA modifications. In this study, we focused on the chikungunya virus...
2.
Baquero-Perez B, Yonchev I, Delgado-Tejedor A, Medina R, Puig-Torrents M, Sudbery I, et al.
Nat Commun . 2024 Mar; 15(1):1964. PMID: 38467633
Despite the nuclear localization of the mA machinery, the genomes of multiple exclusively-cytoplasmic RNA viruses, such as chikungunya (CHIKV) and dengue (DENV), are reported to be extensively mA-modified. However, these...
3.
Manners O, Baquero-Perez B, Mottram T, Yonchev I, Trevelyan C, Harper K, et al.
Viruses . 2023 Jun; 15(6). PMID: 37376680
The epitranscriptomic modification -methyladenosine (mA) is a ubiquitous feature of the mammalian transcriptome. It modulates mRNA fate and dynamics to exert regulatory control over numerous cellular processes and disease pathways,...
4.
Baquero-Perez B, Geers D, Diez J
Viruses . 2021 Jul; 13(6). PMID: 34205979
There are over 100 different chemical RNA modifications, collectively known as the epitranscriptome. -methyladenosine (mA) is the most commonly found internal RNA modification in cellular mRNAs where it plays important...
5.
Baquero-Perez B, Antanaviciute A, Yonchev I, Carr I, Wilson S, Whitehouse A
Elife . 2019 Oct; 8. PMID: 31647415
-methyladenosine (mA) is the most abundant internal RNA modification of cellular mRNAs. mA is recognised by YTH domain-containing proteins, which selectively bind to mA-decorated RNAs regulating their turnover and translation....
6.
Manners O, Baquero-Perez B, Whitehouse A
Biochim Biophys Acta Gene Regul Mech . 2018 Nov; 1862(3):370-381. PMID: 30412798
N-methyladenosine (mA) is a highly pervasive and dynamic modification found on eukaryotic RNA. Despite the failure to comprehend the true regulatory potential of this epitranscriptomic mark for decades, our knowledge...
7.
Antanaviciute A, Baquero-Perez B, Watson C, Harrison S, Lascelles C, Crinnion L, et al.
RNA . 2017 Jul; 23(10):1493-1501. PMID: 28724534
Recent methods for transcriptome-wide -methyladenosine (mA) profiling have facilitated investigations into the RNA methylome and established mA as a dynamic modification that has critical regulatory roles in gene expression and...
8.
Schumann S, Baquero-Perez B, Whitehouse A
J Gen Virol . 2016 May; 97(8):1904-1910. PMID: 27189710
The coupling of mRNA processing steps is essential for precise and efficient gene expression. The human transcription/export (hTREX) complex is a highly conserved multi-protein complex responsible for eukaryotic mRNA stability...
9.
Baquero-Perez B, Whitehouse A
PLoS Pathog . 2015 Nov; 11(11):e1005274. PMID: 26587836
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic herpesvirus associated with various AIDS-related malignancies. Like other herpesviruses, multiple processes required for KSHV lytic replication, including viral transcription, viral DNA synthesis and...
10.
Hughes D, Wood J, Jackson B, Baquero-Perez B, Whitehouse A
PLoS Pathog . 2015 Mar; 11(3):e1004771. PMID: 25794275
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients. For many non-viral malignancies, therapeutically...