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Belen Lopez-Millan

Explore the profile of Belen Lopez-Millan including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 182
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Recent Articles
1.
Lopez-Millan B, Rubio-Gayarre A, Vinyoles M, Trincado J, Fraga M, Fernandez-Fuentes N, et al.
Blood . 2024 Aug; 144(19):2002-2017. PMID: 39093982
B-cell acute lymphoblastic leukemia (B-ALL) is the most common pediatric cancer, with long-term overall survival rates of ∼85%. However, B-ALL harboring rearrangements of the MLL gene (also known as KMT2A),...
2.
Ramos-Muntada M, Trincado J, Blanco J, Bueno C, Rodriguez-Cortez V, Bataller A, et al.
Mol Oncol . 2022 Jun; 16(16):2899-2919. PMID: 35726693
B-cell acute lymphoblastic leukemia (B-ALL) is the commonest childhood cancer. High hyperdiploidy (HHD) identifies the most frequent cytogenetic subgroup in childhood B-ALL. Although hyperdiploidy represents an important prognostic factor in...
3.
Romecin P, Vinyoles M, Lopez-Millan B, de la Guardia R, Atucha N, Querol S, et al.
Stem Cells Transl Med . 2022 May; 11(1):88-96. PMID: 35641173
Mesenchymal stromal stem/cells (MSC) therapies are clinically used in a wide range of disorders based on their robust HLA-independent immunosuppressive and anti-inflammatory properties. However, the mechanisms underlying MSC therapeutic activity...
4.
Lopez-Millan B, Costales P, Gutierrez-Aguera F, de la Guardia R, Roca-Ho H, Vinyoles M, et al.
Cancers (Basel) . 2022 Mar; 14(6). PMID: 35326743
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. Patients with AML harboring a constitutively active internal tandem duplication mutation (ITD) in the FMS-like kinase tyrosine kinase...
5.
de la Guardia R, Velasco-Hernandez T, Gutierrez-Aguera F, Roca-Ho H, Molina O, Nombela-Arrieta C, et al.
Blood Adv . 2021 Sep; 5(23):4842-4854. PMID: 34470043
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. Disease heterogeneity is well documented, and patient stratification determines treatment decisions. Patient-derived xenografts (PDXs) from risk-stratified AML are...
6.
Petazzi P, Torres-Ruiz R, Fidanza A, Roca-Ho H, Gutierrez-Aguera F, Castano J, et al.
Mol Ther Nucleic Acids . 2020 Mar; 20:196-204. PMID: 32171171
Human pluripotent stem cells (hPSCs) and mesenchymal stromal/stem cells (hMSCs) are clinically relevant sources for cellular therapies and for modeling human development and disease. Many stem cell-based applications rely on...
7.
de la Guardia R, Gonzalez-Silva L, Lopez-Millan B, Rodriguez-Sevilla J, Baroni M, Bueno C, et al.
Genes (Basel) . 2020 Jan; 11(1). PMID: 31936647
The cell-of-origin of - and -mutated acute myeloid leukemia (AML) is still a matter of debate. Here, we combined in vitro clonogenic assays with targeted sequencing to gain further insights...
8.
Lopez-Millan B, Sanchez-Martinez D, Roca-Ho H, Gutierrez-Aguera F, Molina O, de la Guardia R, et al.
Leukemia . 2019 Jan; 33(7):1557-1569. PMID: 30635633
B cell acute lymphoblastic leukemia (B-ALL) is the most common childhood cancer, with cure rates of ∼80%. MLL-rearranged (MLLr) B-ALL (MLLr-B-ALL) has, however, an unfavorable prognosis with common therapy refractoriness...
9.
de la Guardia R, Lopez-Millan B, Roca-Ho H, Bueno C, Gutierrez-Aguera F, Fuster J, et al.
Haematologica . 2018 Sep; 104(2):e54-e58. PMID: 30237260
No abstract available.
10.
Lopez-Millan B, de la Guardia R, Roca-Ho H, Anguita E, Islam A, Romero-Moya D, et al.
Oncoimmunology . 2018 Sep; 7(9):e1477460. PMID: 30228947
Treatment for acute myeloid leukemia (AML) remains suboptimal and many patients remain refractory or relapse upon standard chemotherapy based on nucleoside analogs plus anthracyclines. The crosstalk between AML cells and...