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Bei-Qin Yu

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Articles 13
Citations 217
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Recent Articles
1.
Pei Y, Tao R, Li J, Su L, Yu B, Wu X, et al.
Oncotarget . 2016 Apr; 7(21):31322-35. PMID: 27121319
Ten-Eleven Translocation 1 (TET1) is a member of ten eleven translocation enzymes, which convert 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC). TET1 can promote CpG islands demethylation in specific genes and often...
2.
Li P, Shan J, Chen X, Zhang D, Su L, Huang X, et al.
Cell Res . 2015 Apr; 25(5):588-603. PMID: 25916550
Tumor initiation and growth depend on its microenvironment in which cancer-associated fibroblasts (CAFs) in tumor stroma play an important role. Prostaglandin E2 (PGE2) and interleukin (IL)-6 signal pathways are involved...
3.
Zhang B, Du T, Zang M, Chang Q, Fan Z, Li J, et al.
Oncotarget . 2014 Oct; 5(21):10584-95. PMID: 25301736
Androgen receptor (AR) plays an important role in many kinds of cancers. However, the molecular mechanisms of AR in gastric cancer (GC) are poorly characterized. Here, we investigated the role...
4.
Zheng Z, He X, Li J, Yu B, Chen X, Ji J, et al.
Oncol Lett . 2012 Dec; 5(1):255-260. PMID: 23255931
Resistance to 5-fluorouracil (5-FU) in patients with gastric cancer is a serious therapeutic problem and major efforts are underway to understand the underlying mechanisms. We have previously identified RhoGDI2 as...
5.
Yu B, Su L, Li J, Cai Q, Yan M, Chen X, et al.
Mol Med Rep . 2012 Jul; 6(4):821-6. PMID: 22842726
micrornas (miRNAs) play an important role in a wide range of physiological and developmental processes by negatively regulating the expression of target genes at the post-transcriptional level. In this study,...
6.
Li J, Zheng Z, Yu B, Qu Y, Zhu Z, Liu B
Zhonghua Wei Chang Wai Ke Za Zhi . 2012 Apr; 15(4):388-91. PMID: 22539389
Objective: To identify novel multi-drug resistance-related genes, and to explore the mechanisms of multi-drug resistance. Methods: Multi-drug resistant cell line Lovo/5-FU was established by incubation with increasing dose of 5-FU....
7.
Lei K, Wang Y, Wang Q, He X, Liu B, Chen X, et al.
Zhonghua Wei Chang Wai Ke Za Zhi . 2012 Feb; 15(2):169-73. PMID: 22368027
Objective: To explore the interaction between SerpinB5 and MAFbx in gastric cancer cell and to identify the interaction sites. Methods: The interaction between SerpinB5 and MAFbx was screened and validated...
8.
Lei K, Liu B, Wang Y, Chen X, Yu B, Guo Y, et al.
Oncol Rep . 2011 Jul; 26(5):1115-20. PMID: 21725612
Mammary serine protease inhibitor B5 (SerpinB5) is a potential oncogene in gastric cancer (GC); however, the molecular mechanism by which SerpinB5 promotes oncogenesis remains elusive. In this study, SerpinB5-associated proteins...
9.
Chen L, Lan B, Chen X, Li J, Qu Y, Yu B, et al.
Hepatogastroenterology . 2011 Jun; 58(106):674-81. PMID: 21661451
Background/aims: To investigate the cell cycle dependent genes involved in gastric tumorigenesis, possibly determining the relationship between the cell cycle and tumorigenesis. Methodology: MKN45 cells were collected every hour from...
10.
Ke S, Chen X, Zhu Z, Li J, Yu B, Gu Q, et al.
Chin Med J (Engl) . 2010 Dec; 123(22):3193-9. PMID: 21163114
Background: Genetic modification of dendritic cells (DCs) has been used as an effective approach to enhance anti-tumor immunity. RNA interference (RNAi), which can cause the degradation of any RNA in...