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Beatriz Cubelos

Explore the profile of Beatriz Cubelos including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 834
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Recent Articles
1.
Alcover-Sanchez B, Garcia-Martin G, Paleo-Garcia V, Quintas A, Dopazo A, Gruart A, et al.
Glia . 2024 Nov; 73(4):701-719. PMID: 39558879
In the mammalian central nervous system, axonal myelination, executed by mature oligodendrocytes (MOLs), enables rapid neural transmission. Conversely, myelin deficiencies are hallmark features of multiple sclerosis, optic neuromyelitis, and some...
2.
Garcia-Martin G, Sanz-Rodriguez M, Alcover-Sanchez B, Pereira M, Wandosell F, Cubelos B
Int J Mol Sci . 2022 Jan; 23(2). PMID: 35055164
Since the optic nerve is one of the most myelinated tracts in the central nervous system (CNS), many myelin diseases affect the visual system. In this sense, our laboratory has...
3.
Garcia-Martin G, Alcover-Sanchez B, Wandosell F, Cubelos B
Curr Neuropharmacol . 2021 Jun; 20(4):751-765. PMID: 34151767
Brain ischemia, also known as ischemic stroke, occurs when there is a lack of blood supply into the brain. When an ischemic insult appears, both neurons and glial cells can...
4.
Alcover-Sanchez B, Garcia-Martin G, Escudero-Ramirez J, Gonzalez-Riano C, Lorenzo P, Gimenez-Cassina A, et al.
Glia . 2020 Oct; 69(3):619-637. PMID: 33010069
Fast synaptic transmission in vertebrates is critically dependent on myelin for insulation and metabolic support. Myelin is produced by oligodendrocytes (OLs) that maintain multilayered membrane compartments that wrap around axonal...
5.
Alcover-Sanchez B, Garcia-Martin G, Wandosell F, Cubelos B
Int J Mol Sci . 2020 Aug; 21(16). PMID: 32824627
Myelination is required for fast and efficient synaptic transmission in vertebrates. In the central nervous system, oligodendrocytes are responsible for creating myelin sheaths that isolate and protect axons, even throughout...
6.
Sanz-Rodriguez M, Gruart A, Escudero-Ramirez J, de Castro F, Delgado-Garcia J, Wandosell F, et al.
J Neurosci . 2018 May; 38(22):5096-5110. PMID: 29720552
Rapid and effective neural transmission of information requires correct axonal myelination. Modifications in myelination alter axonal capacity to transmit electric impulses and enable pathological conditions. In the CNS, oligodendrocytes (OLs)...
7.
Gonzalez-Riano C, Sanz-Rodriguez M, Escudero-Ramirez J, Lorenzo M, Barbas C, Cubelos B, et al.
J Pharm Biomed Anal . 2018 Feb; 153:44-56. PMID: 29459235
The optic nerve is made of highly specialized neurons and the energetic supply to their axons is crucial due to their great demand. The energy comes basically through the oxidative...
8.
Doan R, Bae B, Cubelos B, Chang C, Hossain A, Al-Saad S, et al.
Cell . 2016 Sep; 167(2):341-354.e12. PMID: 27667684
Comparative analyses have identified genomic regions potentially involved in human evolution but do not directly assess function. Human accelerated regions (HARs) represent conserved genomic loci with elevated divergence in humans....
9.
Cubelos B, Briz C, Esteban-Ortega G, Nieto M
Dev Neurobiol . 2014 Jul; 75(2):163-72. PMID: 25059644
A number of recent reports implicate the differential regulation of apical and basal dendrites in autism disorders and in the higher functions of the human brain. They show that apical...
10.
Merino J, Bellver-Landete V, Oset-Gasque M, Cubelos B
J Cell Physiol . 2014 Jun; 230(1):27-42. PMID: 24913264
In the adult brain, neural progenitor cells (NPCs) reside in the subventricular zone (SVZ) of the lateral ventricles, the dentate gyrus and the olfactory bulb. Following CNS insult, NPCs from...