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Beate Sodeik

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Articles 82
Citations 2427
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Recent Articles
1.
Richardo T, Liu X, Dohner K, Chao T, Buch A, Binz A, et al.
J Virol . 2025 Feb; :e0163824. PMID: 39945537
Importance: This study describes a novel murine skin explant model to investigate early events in HSV-1 infection without causing significant tissue damage. To infect from the outside, via the apical...
2.
Moschonas G, Delhaye L, Cooreman R, Husers F, Bhat A, Stylianidou Z, et al.
Cell Host Microbe . 2024 Oct; 32(10):1705-1724.e14. PMID: 39389033
Human myxovirus resistance 2 (MX2) can restrict HIV-1 and herpesviruses at a post-entry step through a process requiring an interaction between MX2 and the viral capsids. The involvement of other...
3.
Zeitvogel J, Dohner K, Klug I, Rademacher F, Glaser R, Sodeik B, et al.
J Med Virol . 2024 Oct; 96(10):e29942. PMID: 39360648
Approximately 22% of moderately to severely affected atopic dermatitis (AD) patients have a history of eczema herpeticum, a disseminated rash primarily caused by herpes simplex virus type 1 (HSV-1). Reduced...
4.
Zeitvogel J, Dohner K, Klug I, Richardo T, Sodeik B, Werfel T
J Med Virol . 2024 Sep; 96(9):e29865. PMID: 39233492
Eczema herpeticum (EH) is a disseminated severe herpes simplex virus type 1 (HSV-1) infection that mainly occurs in a subset of patients suffering from atopic dermatitis (AD). EH is complex...
5.
Dohner K, Serrero M, Viejo-Borbolla A, Sodeik B
Annu Rev Virol . 2024 Jul; 11(1):215-238. PMID: 38954634
The nucleoplasm, the cytosol, the inside of virions, and again the cytosol comprise the world in which the capsids of alphaherpesviruses encounter viral and host proteins that support or limit...
6.
Sun G, Kropp K, Kirchner M, Pluckebaum N, Selich A, Serrero M, et al.
mBio . 2024 Jan; 15(2):e0330823. PMID: 38275838
The highly prevalent herpes simplex virus type 1 (HSV-1) causes a range of diseases, including cold sores, blinding keratitis, and life-threatening encephalitis. HSV-1 initially replicates in epithelial cells, enters the...
7.
Dohner K, Serrero M, Sodeik B
Curr Opin Virol . 2023 Sep; 62:101361. PMID: 37672874
Microtubule transport and nuclear import are functionally connected, and the nuclear pore complex (NPC) can interact with microtubule motors. For several alphaherpesvirus proteins, nuclear localization signals (NLSs) and their interactions...
8.
Mohnke J, Stark I, Fischer M, Fischer P, Schlosser A, Grothey A, et al.
J Virol . 2022 Oct; 96(22):e0096322. PMID: 36314822
The evolutionarily conserved, structural HSV-1 tegument protein pUL36 is essential for both virus entry and assembly. While its N-terminal deubiquitinase (DUB) activity is dispensable for infection in cell culture, it...
9.
Kazmierski J, Elsner C, Dohner K, Xu S, Ducroux A, Pott F, et al.
J Immunol . 2022 Jul; 209(3):535-547. PMID: 35851540
Upon recognition of aberrantly located DNA, the innate immune sensor cyclic GMP-AMP synthase (cGAS) activates stimulator of IFN genes (STING)/IFN regulatory factor (IRF)3-driven antiviral responses. In this study, we characterized...
10.
Serrero M, Girault V, Weigang S, Greco T, Ramos-Nascimento A, Anderson F, et al.
Elife . 2022 Apr; 11. PMID: 35475759
Host proteins sense viral products and induce defence mechanisms, particularly in immune cells. Using cell-free assays and quantitative mass spectrometry, we determined the interactome of capsid-host protein complexes of herpes...