Beate Kehrel
Overview
Explore the profile of Beate Kehrel including associated specialties, affiliations and a list of published articles.
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9
Citations
352
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Recent Articles
1.
Hoepner G, Althaus K, Muller J, Zieger B, Pavlova A, Boeckelmann D, et al.
Hamostaseologie
. 2025 Jan;
PMID: 39870109
In this article, our goal is to offer an introduction and overview of the diagnostic approach to inherited platelet function defects (iPFDs) for clinicians and laboratory personnel who are beginning...
2.
Althaus K, Hoepner G, Zieger B, Pruller F, Pavlova A, Boeckelmann D, et al.
Hamostaseologie
. 2025 Jan;
PMID: 39870108
Congenital platelet disorders are rare and targeted treatment is usually not possible. Inherited platelet function disorders (iPFDs) can affect surface receptors and multiple platelet responses such as defects of platelet...
3.
Bhogal P, Lenz-Habijan T, Bannewitz C, Hannes R, Monstadt H, Brodde M, et al.
Interv Neuroradiol
. 2020 May;
26(4):488-493.
PMID: 32366150
Objectives: The implantation of flow diverters, or stents in general, necessitates the use of dual anti-platelet treatment with typical regimes including aspirin and a P2Y12 inhibitor. This carries an inherent...
4.
Boncler M, Kehrel B, Szewczyk R, Stec-Martyna E, Bednarek R, Brodde M, et al.
Int J Biol Macromol
. 2017 Nov;
107(Pt B):2701-2714.
PMID: 29111269
We examined the structural and functional consequences of oxidative modification of C-reactive protein (CRP) by hypochlorous acid (HOCl), which can be generated in vivo via the myeloperoxidase/HO/Cl system. HOCl exposure...
5.
Gobel K, Pankratz S, Asaridou C, Herrmann A, Bittner S, Merker M, et al.
Nat Commun
. 2016 May;
7:11626.
PMID: 27188843
Aberrant immune responses represent the underlying cause of central nervous system (CNS) autoimmunity, including multiple sclerosis (MS). Recent evidence implicated the crosstalk between coagulation and immunity in CNS autoimmunity. Here...
6.
Brodde M, Muller A, Kehrel B
Transfus Med Hemother
. 2014 May;
41(2):140-4.
PMID: 24847190
Background: We previously identified protein impurities in plasma-derived factor VIII (pdFVIII) products. The goal of the current experiments was to determine whether these impurities might have clinical relevance, by comparing...
7.
Kehrel B
Anasthesiol Intensivmed Notfallmed Schmerzther
. 2011 May;
46(5):318-22.
PMID: 21560095
Diagnostic point of care testing based on thrombelastometry with the aim to fully understand the overall changes in global haemostasis during the perioperative phase is today performed in several operating...
8.
Kupper S, Mees S, Gassmann P, Brodde M, Kehrel B, Haier J
Shock
. 2007 Jun;
28(3):300-8.
PMID: 17545948
Growing evidence supports substantial pathophysiological impact of platelets and their interactions on the development of septic lung failure. We developed a rat model of endotoxemia for direct in situ visualization...
9.
Scharte M, Jurk K, Kehrel B, Zarbock A, Van Aken H, Singbartl K
FEBS Lett
. 2006 Nov;
580(27):6399-404.
PMID: 17097641
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that mediates the adaptive response to hypoxia. Increasing evidence suggests a crucial role for HIF-1 in immune reactions. Here we investigated the effect...
10.
Viemann D, Strey A, Janning A, Jurk K, Klimmek K, Vogl T, et al.
Blood
. 2004 Dec;
105(7):2955-62.
PMID: 15598812
Myeloid-related protein 8 (MRP8) and MRP14, S100 proteins secreted by activated phagocytes, bind specifically to endothelial cells. The endothelial response to MRP8/MRP14, however, is unknown. Using oligonucleotide microarray analysis, we...