Basappa Basappa
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Explore the profile of Basappa Basappa including associated specialties, affiliations and a list of published articles.
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35
Citations
79
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Recent Articles
11.
Kim N, Dukanya D, Sethi G, Girimanchanaika S, Yang J, Nagaraja O, et al.
Transl Oncol
. 2024 Aug;
49:102101.
PMID: 39159553
Small molecule-driven JNK activation has been found to induce apoptosis and paraptosis in cancer cells. Herein pharmacological effects of synthetic oxazine (4aS, 7aS)-3-((4-(4‑chloro-2-fluorophenyl)piperazin-1-yl)methyl)-4-phenyl-4, 4a, 5, 6, 7, 7a-hexahydrocyclopenta[e] [1,2]oxazine (FPPO;...
12.
Zhu B, Gu H, Mao Z, Beeraka N, Zhao X, Anand M, et al.
J Glob Health
. 2024 Aug;
14:04155.
PMID: 39148469
Background: The incidence and mortality of gynaecological cancers can significantly impact women's quality of life and increase the health care burden for organisations globally. The objective of this study was...
13.
Yuan J, Narasimhachar B, Ravish A, Yang L, Zhang H, Wang Q, et al.
Front Oncol
. 2024 Aug;
14:1390992.
PMID: 39135991
Introduction: Nuclear factor kappa (NF-κB) plays a key role in cancer cell proliferation; thus, small molecule inhibitors of NF-κB activity can effectively inhibit breast cancer (BC) progression. We have previously...
14.
Yang M, Basappa B, Deveshegowda S, Ravish A, Mohan A, Nagaraja O, et al.
J Adv Res
. 2024 Jul;
PMID: 39067696
Introduction: Globally, colorectal cancer (CRC) is the third most common type of cancer, and its treatment frequently includes the utilization of drugs based on antibodies and small molecules. The development...
15.
Cao Y, Lu C, Beeraka N, Efetov S, Enikeev M, Fu Y, et al.
Front Immunol
. 2024 Jul;
15:1428920.
PMID: 39015566
Ferroptosis induces significant changes in mitochondrial morphology, including membrane condensation, volume reduction, cristae alteration, and outer membrane rupture, affecting mitochondrial function and cellular fate. Recent reports have described the intrinsic...
16.
Guo Q, Ma S, Zhao D, Beeraka N, Gu H, Zheng Y, et al.
World J Oncol
. 2024 Jul;
15(4):598-611.
PMID: 38993244
Background: Impact of radiotherapy (RT) for esophageal cancer (EC) patients on the development of secondary head and neck cancer (SHNC) remains equivocal. The objective of this study was to investigate...
17.
Beeraka N, Basappa B, Nikolenko V, Mahesh P
Stem Cell Rev Rep
. 2024 Jul;
21(1):2-27.
PMID: 38976142
Haematopoiesis within the bone marrow (BM) represents a complex and dynamic process intricately regulated by neural signaling pathways. This delicate orchestration is susceptible to disruption by factors such as aging,...
18.
Tan Y, Sun B, Zhang X, Zhang S, Guo H, Basappa B, et al.
Cell Death Dis
. 2024 Feb;
15(2):173.
PMID: 38409090
Therapeutic targeting of KRAS-mutant pancreatic ductal adenocarcinoma (PDAC) has remained a significant challenge in clinical oncology. Direct targeting of KRAS has proven difficult, and inhibition of the KRAS effectors have...
19.
Parameshwaraiah S, Shivakumar R, Xi Z, Siddappa T, Ravish A, Mohan A, et al.
Chem Biodivers
. 2024 Jan;
21(3):e202301950.
PMID: 38258537
The increased expression of VEGFR-2 in a variety of cancer cells promotes a cascade of cellular responses that improve cell survival, growth, and proliferation. Heterocycles are common structural elements in...
20.
Tan Y, Chiou Y, Guo H, Zhang S, Huang X, Dukanya D, et al.
NPJ Precis Oncol
. 2024 Jan;
8(1):8.
PMID: 38200104
Aberrant activation of the PI3K/AKT signaling axis along with the sustained phosphorylation of downstream BAD is associated with a poor outcome of TNBC. Herein, the phosphorylated to non-phosphorylated ratio of...