Bas Vastert
Overview
Explore the profile of Bas Vastert including associated specialties, affiliations and a list of published articles.
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14
Citations
471
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0
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Recent Articles
1.
Mocholi E, Corrigan E, Chalkiadakis T, Gulersonmez C, Stigter E, Vastert B, et al.
Cell Rep
. 2025 Feb;
44(2):115287.
PMID: 40009514
Juvenile idiopathic arthritis (JIA) is an autoimmune disease characterized by accumulation of activated CD4 T cells in the synovial fluid (SF) of affected joints. JIA CD4 T cells exhibit a...
2.
NRF2/Itaconate Axis Regulates Metabolism and Inflammatory Properties of T Cells in Children with JIA
Rajendiran A, Subramanyam S, Klemm P, Jankowski V, van Loosdregt J, Vastert B, et al.
Antioxidants (Basel)
. 2022 Dec;
11(12).
PMID: 36552634
Background: CD4+ T cells critically contribute to the initiation and perturbation of inflammation. When CD4+ T cells enter inflamed tissues, they adapt to hypoxia and oxidative stress conditions, and to...
3.
Ververs F, Engelen S, Nuboer R, Vastert B, van der Ent C, Vant Land B, et al.
Sci Rep
. 2021 Oct;
11(1):20082.
PMID: 34635725
Invariant Natural Killer T (iNKT) cells respond to the ligation of lipid antigen-CD1d complexes via their T-cell receptor and are implicated in various immunometabolic diseases. We considered that immunometabolic factors...
4.
Jeyaratnam J, Simon A, Calvo I, Constantin T, Shcherbina A, Hofer M, et al.
Rheumatology (Oxford)
. 2021 Sep;
61(5):2088-2094.
PMID: 34554243
Objectives: To evaluate the long-term efficacy and safety of canakinumab in patients with mevalonate kinase deficiency during the open label extension (weeks 41-113) of the randomized controlled CLUSTER trial. Methods:...
5.
Maschmeyer P, Heinz G, Skopnik C, Lutter L, Mazzoni A, Heinrich F, et al.
Eur J Immunol
. 2020 Dec;
51(4):915-929.
PMID: 33296081
T lymphocytes accumulate in inflamed tissues of patients with chronic inflammatory diseases (CIDs) and express pro-inflammatory cytokines upon re-stimulation in vitro. Further, a significant genetic linkage to MHC genes suggests...
6.
de Graeff N, Groot N, Brogan P, Ozen S, Avcin T, Bader-Meunier B, et al.
Rheumatology (Oxford)
. 2020 Feb;
59(4):919.
PMID: 32073621
No abstract available.
7.
Ozen S, Marks S, Brogan P, Groot N, de Graeff N, Avcin T, et al.
Rheumatology (Oxford)
. 2019 Mar;
58(9):1607-1616.
PMID: 30879080
Objectives: IgA vasculitis (IgAV, formerly known as Henoch-Schönlein purpura) is the most common cause of systemic vasculitis in childhood. To date, there are no internationally agreed, evidence-based guidelines concerning the...
8.
de Graeff N, Groot N, Brogan P, Ozen S, Avcin T, Bader-Meunier B, et al.
Rheumatology (Oxford)
. 2018 Dec;
58(4):656-671.
PMID: 30535249
Objectives: The European initiative Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) aimed to optimize care for children with rheumatic diseases. Systemic vasculitides are very rare in...
9.
de Graeff N, Groot N, Ozen S, Eleftheriou D, Avcin T, Bader-Meunier B, et al.
Rheumatology (Oxford)
. 2018 Dec;
58(4):672-682.
PMID: 30535127
Objectives: The European Single Hub and Access point for paediatric Rheumatology in Europe initiative aimed to optimize care for children with rheumatic diseases. Kawasaki disease (KD) is the most common...
10.
Hugle B, Schippers A, Fischer N, Ohl K, Denecke B, Ticconi F, et al.
Arthritis Res Ther
. 2018 Jun;
20(1):98.
PMID: 29848367
Background: The term systemic juvenile idiopathic arthritis (sJIA) describes an autoinflammatory condition characterized by arthritis and severe systemic inflammation, which in later stages can transform into interleukin (IL)-17-driven autoimmune arthritis....