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Barry Slobedman

Explore the profile of Barry Slobedman including associated specialties, affiliations and a list of published articles. Areas
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Articles 82
Citations 1931
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Recent Articles
11.
Ashley C, McSharry B, McWilliam H, Stanton R, Fielding C, Mathias R, et al.
Front Immunol . 2023 Feb; 14:1107497. PMID: 36845106
Introduction: The antigen presentation molecule MHC class I related protein-1 (MR1) is best characterized by its ability to present bacterially derived metabolites of vitamin B2 biosynthesis to mucosal-associated invariant T-cells...
12.
Steain M, Slobedman B, Abendroth A
Curr Top Microbiol Immunol . 2022 May; 438:59-73. PMID: 35624346
Like other herpesviruses, varicella-zoster virus (VZV) evolved a wide range of functions to modulate a broad array of host defences, presumably as a means to provide a survival advantage to...
13.
Stern L, McGuire H, Avdic S, Fazekas de St. Groth B, Gottlieb D, Abendroth A, et al.
Nat Commun . 2022 May; 13(1):2603. PMID: 35546552
Human cytomegalovirus reactivation is a major opportunistic infection after allogeneic haematopoietic stem cell transplantation and has a complex relationship with post-transplant immune reconstitution. Here, we use mass cytometry to define...
14.
Samer C, Traves R, Purohit S, Abendroth A, McWilliam H, Slobedman B
Crit Rev Immunol . 2022 Apr; 41(5):49-67. PMID: 35381139
Mucosal-associated invariant T (MAIT) cells are abundant innate-like T cells important in antimicrobial immunity. These cells express a semi-invariant T cell receptor that recognizes the Major Histocompatibility Complex (MHC) class...
15.
Abendroth A, Slobedman B
Curr Top Microbiol Immunol . 2022 Mar; 438:85-102. PMID: 35332385
Varicella zoster virus (VZV) is a medically important human herpesvirus that has co-evolved with the human host to become a highly successful and ubiquitous pathogen. Whilst it is clear the...
16.
Purohit S, Samer C, McWilliam H, Traves R, Steain M, McSharry B, et al.
J Infect Dis . 2021 Oct; 227(3):391-401. PMID: 34648018
The antigen presentation molecule MR1 (major histocompatibility complex, class I-related) presents ligands derived from the riboflavin (vitamin B) synthesis pathway, which is not present in mammalian species or viruses, to...
17.
Bernshtein B, Nachshon A, Shnayder M, Stern L, Avdic S, Blyth E, et al.
Front Cell Infect Microbiol . 2021 Jan; 10:607470. PMID: 33489936
Human cytomegalovirus (HCMV) is a widespread pathogen establishing a latent infection in its host. HCMV reactivation is a major health burden in immunocompromised individuals, and is a major cause of...
18.
Abendroth A, Slobedman B
J Infect Dis . 2020 Sep; 223(1):4-6. PMID: 32901280
No abstract available.
19.
Steain M, Baker M, Pham C, Shanmugam N, Gambin Y, Sierecki E, et al.
PLoS Pathog . 2020 Jul; 16(7):e1008473. PMID: 32649716
Herpesviruses are known to encode a number of inhibitors of host cell death, including RIP Homotypic Interaction Motif (RHIM)-containing proteins. Varicella zoster virus (VZV) is a member of the alphaherpesvirus...
20.
McGuire H, Rizzetto S, Withers B, Clancy L, Avdic S, Stern L, et al.
Clin Transl Immunology . 2020 Jul; 9(7):e1149. PMID: 32642063
Objectives: Cytomegalovirus (CMV) is known to have a significant impact on immune recovery post-allogeneic haemopoietic stem cell transplant (HSCT). Adoptive therapy with donor-derived or third-party virus-specific T cells (VST) can...