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Barbora Knoppova

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Recent Articles
1.
Liu L, Khan A, Sanchez-Rodriguez E, Zanoni F, Li Y, Steers N, et al.
Nat Commun . 2023 Feb; 14(1):655. PMID: 36746961
No abstract available.
2.
Liu L, Khan A, Sanchez-Rodriguez E, Zanoni F, Li Y, Steers N, et al.
Nat Commun . 2022 Nov; 13(1):6859. PMID: 36369178
Immunoglobulin A (IgA) mediates mucosal responses to food antigens and the intestinal microbiome and is involved in susceptibility to mucosal pathogens, celiac disease, inflammatory bowel disease, and IgA nephropathy. We...
3.
Knoppova B, Reily C, King R, Julian B, Novak J, Green T
J Clin Med . 2021 Oct; 10(19). PMID: 34640530
IgA nephropathy, initially described in 1968 as a kidney disease with glomerular "intercapillary deposits of IgA-IgG", has no disease-specific treatment and is a common cause of kidney failure. Clinical observations...
4.
Moldoveanu Z, Suzuki H, Reily C, Satake K, Novak L, Xu N, et al.
J Autoimmun . 2021 Jan; 118:102593. PMID: 33508637
Background: IgA nephropathy is thought to be an autoimmune disease wherein galactose-deficient IgA1 (Gd-IgA1) is recognized by IgG autoantibodies, resulting in formation and renal accumulation of nephritogenic immune complexes. Although...
5.
Wei Q, Hargett A, Knoppova B, Duverger A, Rawi R, Shen C, et al.
iScience . 2020 Nov; 23(11):101711. PMID: 33205023
HIV-1 envelope (Env) N-glycosylation impact virus-cell entry and immune evasion. How each glycan interacts to shape the Env-protein-sugar complex and affects Env function is not well understood. Here, analysis of...
6.
Rizk D, Maillard N, Julian B, Knoppova B, Green T, Novak J, et al.
Front Immunol . 2019 Apr; 10:504. PMID: 30941137
IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and a common cause of end-stage renal disease. Evaluation of a kidney biopsy is necessary for diagnosis, with...
7.
Hargett A, Wei Q, Knoppova B, Hall S, Huang Z, Prakash A, et al.
J Virol . 2018 Oct; 93(1). PMID: 30305355
The HIV-1 envelope (Env) glycans shield the surface of Env from the immune system and form integral interactions important for a functional Env. To understand how individual N-glycosylation sites (NGS)...
8.
Lafayette R, Canetta P, Rovin B, Appel G, Novak J, Nath K, et al.
J Am Soc Nephrol . 2016 Nov; 28(4):1306-1313. PMID: 27821627
IgA nephropathy frequently leads to progressive CKD. Although interest surrounds use of immunosuppressive agents added to standard therapy, several recent studies have questioned efficacy of these agents. Depleting antibody-producing B...
9.
Knoppova B, Reily C, Maillard N, Rizk D, Moldoveanu Z, Mestecky J, et al.
Front Immunol . 2016 May; 7:117. PMID: 27148252
IgA nephropathy (IgAN) is the most common primary glomerulonephritis, frequently leading to end-stage renal disease, as there is no disease-specific therapy. IgAN is diagnosed from pathological assessment of a renal...
10.
Vrzal R, Knoppova B, Bachleda P, Dvorak Z
J Biochem Mol Toxicol . 2013 Sep; 27(12):515-21. PMID: 24038852
Sibutramine is a serotonin-norepinephrine reuptake inhibitor that was used for weight-loss management in obese patients. Even though it was officially withdrawn from the market in 2010, it is still present...