Barbel Stecher
Overview
Explore the profile of Barbel Stecher including associated specialties, affiliations and a list of published articles.
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Articles
112
Citations
8906
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Recent Articles
1.
Urbauer E, Aguanno D, Mindermann N, Omer H, Metwaly A, Krammel T, et al.
Cell Host Microbe
. 2024 Jul;
32(8):1347-1364.e10.
PMID: 39013472
Mitochondrial dysfunction is associated with inflammatory bowel diseases (IBDs). To understand how microbial-metabolic circuits contribute to intestinal injury, we disrupt mitochondrial function in the epithelium by deleting the mitochondrial chaperone,...
2.
Intestinal colonization resistance in the context of environmental, host, and microbial determinants
Woelfel S, Silva M, Stecher B
Cell Host Microbe
. 2024 Jun;
32(6):820-836.
PMID: 38870899
Microbial communities that colonize the human gastrointestinal (GI) tract defend against pathogens through a mechanism known as colonization resistance (CR). Advances in technologies such as next-generation sequencing, gnotobiotic mouse models,...
3.
Beutler M, Eberl C, Garzetti D, Herp S, Munch P, Ring D, et al.
Infect Immun
. 2024 Jan;
92(2):e0031823.
PMID: 38189339
Inflammation has a pronounced impact on the intestinal ecosystem by driving an expansion of facultative anaerobic bacteria at the cost of obligate anaerobic microbiota. This pathogen "blooming" is also a...
4.
Ye H, Borusak S, Eberl C, Krasenbrink J, Weiss A, Chen S, et al.
Nat Commun
. 2023 Sep;
14(1):5533.
PMID: 37723166
Taurine-respiring gut bacteria produce HS with ambivalent impact on host health. We report the isolation and ecophysiological characterization of a taurine-respiring mouse gut bacterium. Taurinivorans muris strain LT0009 represents a...
5.
von Strempel A, Weiss A, Wittmann J, Silva M, Ring D, Wortmann E, et al.
PLoS Pathog
. 2023 Aug;
19(8):e1011600.
PMID: 37603558
Gut microbial communities protect the host against a variety of major human gastrointestinal pathogens. Bacteriophages (phages) are ubiquitous in nature and frequently ingested via food and drinking water. Moreover, they...
6.
Weiss A, Niedermeier L, von Strempel A, Burrichter A, Ring D, Meng C, et al.
Nat Commun
. 2023 Aug;
14(1):4780.
PMID: 37553336
A challenging task to understand health and disease-related microbiome signatures is to move beyond descriptive community-level profiling towards disentangling microbial interaction networks. Using a synthetic gut bacterial community, we aimed...
7.
Munch P, Eberl C, Woelfel S, Ring D, Fritz A, Herp S, et al.
Cell Host Microbe
. 2023 Jun;
31(6):1007-1020.e4.
PMID: 37279755
Bacteria can evolve to withstand a wide range of antibiotics (ABs) by using various resistance mechanisms. How ABs affect the ecology of the gut microbiome is still poorly understood. We...
8.
Lamy-Besnier Q, Bignaud A, Garneau J, Titecat M, Conti D, von Strempel A, et al.
Microbiome
. 2023 May;
11(1):111.
PMID: 37208714
Background: Bacteria and their viruses, bacteriophages, are the most abundant entities of the gut microbiota, a complex community of microorganisms associated with human health and disease. In this ecosystem, the...
9.
Mossad O, Nent E, Woltemate S, Folschweiller S, Buescher J, Schnepf D, et al.
Nat Aging
. 2023 Apr;
1(12):1127-1136.
PMID: 37117525
Understanding the physiological origins of age-related cognitive decline is of critical importance given the rising age of the world's population. Previous work in animal models has established a strong link...
10.
Lettl C, Schindele F, Mehdipour A, Steiner T, Ring D, Brack-Werner R, et al.
Cell Chem Biol
. 2023 Apr;
30(5):499-512.e5.
PMID: 37100053
Respiratory complex I is a multicomponent enzyme conserved between eukaryotic cells and many bacteria, which couples oxidation of electron donors and quinone reduction with proton pumping. Here, we report that...