Barbara Sennino
Overview
Explore the profile of Barbara Sennino including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
2170
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0
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Recent Articles
1.
Puig-Saus C, Sennino B, Peng S, Wang C, Pan Z, Yuen B, et al.
Nature
. 2023 Mar;
615(7953):697-704.
PMID: 36890230
Neoantigens are peptides derived from non-synonymous mutations presented by human leukocyte antigens (HLAs), which are recognized by antitumour T cells. The large HLA allele diversity and limiting clinical samples have...
2.
Foy S, Jacoby K, Bota D, Hunter T, Pan Z, Stawiski E, et al.
Nature
. 2022 Nov;
615(7953):687-696.
PMID: 36356599
T cell receptors (TCRs) enable T cells to specifically recognize mutations in cancer cells. Here we developed a clinical-grade approach based on CRISPR-Cas9 non-viral precision genome-editing to simultaneously knockout the...
3.
Kim M, Nitschke M, Sennino B, Murer P, Schriver B, Bell A, et al.
Cancer Res
. 2017 Dec;
78(4):922-937.
PMID: 29259007
Oncolytic viruses pose many questions in their use in cancer therapy. In this study, we assessed the potential of mpJX-594 (mouse-prototype JX-594), a replication-competent vaccinia virus administered by intravenous injection,...
4.
Foy S, Sennino B, Dela Cruz T, Cote J, Gordon E, Kemp F, et al.
PLoS One
. 2016 Feb;
11(2):e0150084.
PMID: 26910562
Poxvirus-based active immunotherapies mediate anti-tumor efficacy by triggering broad and durable Th1 dominated T cell responses against the tumor. While monotherapy significantly delays tumor growth, it often does not lead...
5.
Nejadnik H, Ye D, Lenkov O, Donig J, Martin J, Castillo R, et al.
ACS Nano
. 2015 Jan;
9(2):1150-60.
PMID: 25597243
About 43 million individuals in the U.S. encounter cartilage injuries due to trauma or osteoarthritis, leading to joint pain and functional disability. Matrix-associated stem cell implants (MASI) represent a promising...
6.
Ciamporcero E, Miles K, Adelaiye R, Ramakrishnan S, Shen L, Ku S, et al.
Mol Cancer Ther
. 2014 Nov;
14(1):101-10.
PMID: 25381264
Alternative pathways to the VEGF, such as hepatocyte growth factor or HGF/c-met, are emerging as key players in tumor angiogenesis and resistance to anti-VEGF therapies. The aim of this study...
7.
Khurana A, Chapelin F, Beck G, Lenkov O, Donig J, Nejadnik H, et al.
Radiology
. 2013 Jul;
269(1):186-97.
PMID: 23850832
Purpose: To determine whether intravenous ferumoxytol can be used to effectively label mesenchymal stem cells (MSCs) in vivo and can be used for tracking of stem cell transplants. Materials And...
8.
Sennino B, Ishiguro-Oonuma T, Schriver B, Christensen J, McDonald D
Cancer Res
. 2013 Apr;
73(12):3692-703.
PMID: 23576559
Inhibition of VEGF signaling can promote lymph node metastasis in preclinical models, but the mechanism is not fully understood, and successful methods of prevention have not been found. Signaling of...
9.
Nejadnik H, Henning T, Do T, Sutton E, Baehner F, Horvai A, et al.
PLoS One
. 2012 Dec;
7(12):e49971.
PMID: 23251354
Objectives: The purpose of our study was to assess the chondrogenic potential and the MR signal effects of GadofluorineM-Cy labeled matrix associated stem cell implants (MASI) in pig knee specimen....
10.
Sennino B, McDonald D
Nat Rev Cancer
. 2012 Sep;
12(10):699-709.
PMID: 23001349
Selective inhibition of vascular endothelial growth factor (VEGF) increases the efficacy of chemotherapy and has beneficial effects on multiple advanced cancers, but response is often limited and the disease eventually...