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Barbara M Rothen-Rutishauser

Explore the profile of Barbara M Rothen-Rutishauser including associated specialties, affiliations and a list of published articles. Areas
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Citations 407
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Recent Articles
1.
Seydoux E, Rodriguez-Lorenzo L, Blom R, Stumbles P, Petri-Fink A, Rothen-Rutishauser B, et al.
Nanomedicine . 2016 Mar; 12(7):1815-1826. PMID: 27013126
To address how surface charge affects the fate of potential nanocarriers in the lung, gold nanoparticles (AuNPs) coated with polyvinyl alcohol containing either positively (NH) or negatively (COOH) charged functional...
2.
Schleh C, Rothen-Rutishauser B, Blank F, Lauenstein H, Nassimi M, Krug N, et al.
Respir Res . 2012 Feb; 13:8. PMID: 22296755
Background: Allergen-containing subpollen particles (SPP) are released from whole plant pollen upon contact with water or even high humidity. Because of their size SPP can preferentially reach the lower airways...
3.
Ahmad S, Raemy D, Loader J, Kailey J, Neeves K, White C, et al.
J Aerosol Med Pulm Drug Deliv . 2011 Oct; 25(1):7-15. PMID: 22007674
Background: Nanoparticles (NPs) produced by nanotechnology processes have taken the field of medicine by storm. Concerns about safety of these NPs in humans, however, have recently been raised. Although studies...
4.
Lehmann A, Daum N, Bur M, Lehr C, Gehr P, Rothen-Rutishauser B
Eur J Pharm Biopharm . 2010 Nov; 77(3):398-406. PMID: 21056660
A triple cell co-culture model was recently established by the authors, consisting of either A549 or 16HBE14o- epithelial cells, human blood monocyte-derived macrophages and dendritic cells, which offers the possibility...
5.
Blank F, Wehrli M, Lehmann A, Baum O, Gehr P, von Garnier C, et al.
Immunobiology . 2010 Apr; 216(1-2):86-95. PMID: 20362352
The human airway epithelium serves as structural and functional barrier against inhaled particulate antigen. Previously, we demonstrated in an in vitro epithelial barrier model that monocyte derived dendritic cells (MDDC)...
6.
Lehmann A, Blank F, Baum O, Gehr P, Rothen-Rutishauser B
Part Fibre Toxicol . 2009 Oct; 6:26. PMID: 19814802
Background: Using an in vitro triple cell co-culture model consisting of human epithelial cells (16HBE14o-), monocyte-derived macrophages and dendritic cells, it was recently demonstrated that macrophages and dendritic cells create...
7.
Blank F, Rothen-Rutishauser B, Schurch S, Gehr P
J Aerosol Med . 2006 Oct; 19(3):392-405. PMID: 17034314
As a part of the respiratory tissue barrier, lung epithelial cells play an important role against the penetration of the body by inhaled particulate foreign materials. In most cell culture...
8.
Rothen-Rutishauser B, Schurch S, Haenni B, Kapp N, Gehr P
Environ Sci Technol . 2006 Aug; 40(14):4353-9. PMID: 16903270
So far, little is known about the interaction of nanoparticles with lung cells, the entering of nanoparticles, and their transport through the blood stream to other organs. The entering and...
9.
Gehr P, Blank F, Rothen-Rutishauser B
Paediatr Respir Rev . 2006 Jun; 7 Suppl 1:S73-5. PMID: 16798602
Inhaled particles may cause increased pulmonary and cardiovascular morbidity and mortality. The wall structures of airways and alveoli act as a series of structural and functional barriers against inhaled particles....
10.
Rothen-Rutishauser B, Kiama S, Gehr P
Am J Respir Cell Mol Biol . 2005 Jan; 32(4):281-9. PMID: 15640437
A novel triple co-culture model of the human airway barrier was designed to simulate the cellular part of the air-blood barrier of the respiratory tract represented by macrophages, epithelial cells,...