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Balu Krishnan

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Articles 36
Citations 388
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Recent Articles
1.
Gula J, Slegers R, Van Hoof R, Krishnan B, Mischi M, van Kranen-Mastenbroek V, et al.
Epilepsia . 2025 Jan; PMID: 39831797
Objective: To investigate whether local lesions created by stereo-electroencephalography (SEEG)-guided radiofrequency thermocoagulation (RFTC) affect distant brain connectivity and excitability in patients with focal, drug-resistant epilepsy (DRE). Methods: Ten patients with...
2.
Nieto Ramos A, Krishnan B, Alexopoulos A, Bingaman W, Najm I, Bulacio J, et al.
J Neural Eng . 2024 Aug; 21(4). PMID: 39151464
For medically-refractory epilepsy patients, stereoelectroencephalography (sEEG) is a surgical method using intracranial electrode recordings to identify brain networks participating in early seizure organization and propagation (i.e. the epileptogenic zone, EZ)....
3.
Su T, Choi J, Hu S, Wang X, Blumcke I, Chiprean K, et al.
Ann Neurol . 2024 Aug; 96(5):944-957. PMID: 39096056
Objective: To develop a multiparametric machine-learning (ML) framework using high-resolution 3 dimensional (3D) magnetic resonance (MR) fingerprinting (MRF) data for quantitative characterization of focal cortical dysplasia (FCD). Materials: We included...
4.
Krishnan B, Tousseyn S, Taylor K, Wu G, Serletis D, Najm I, et al.
Clin Neurophysiol . 2024 Mar; 161:80-92. PMID: 38452427
Objective: Ictal Single Photon Emission Computed Tomography (SPECT) and stereo-electroencephalography (SEEG) are diagnostic techniques used for the management of patients with drug-resistant focal epilepsies. While hyperperfusion patterns in ictal SPECT...
5.
Kobayashi K, Taylor K, Shahabi H, Krishnan B, Joshi A, Mackow M, et al.
Brain Commun . 2024 Feb; 6(1):fcae035. PMID: 38390255
Responsive neurostimulation is a closed-loop neuromodulation therapy for drug resistant focal epilepsy. Responsive neurostimulation electrodes are placed near ictal onset zones so as to enable detection of epileptiform activity and...
6.
Bae J, Clay J, Thapa B, Powell D, Turpin H, Tasori Partovi S, et al.
J Vis Exp . 2023 Jul; (196). PMID: 37427958
Simultaneous electroencephalogram and functional magnetic resonance imaging (EEG-fMRI) is a unique combined technique that provides synergy in the understanding and localization of seizure onset in epilepsy. However, reported experimental protocols...
7.
Krishnan B, Tousseyn S, Wang Z, Murakami H, Wu G, Burgess R, et al.
Hum Brain Mapp . 2022 Dec; 44(4):1695-1710. PMID: 36480260
Single-photon emission computed tomography (SPECT) during seizures and magnetoencephalography (MEG) during the interictal state are noninvasive modalities employed in the localization of the epileptogenic zone in patients with drug-resistant focal...
8.
Tang Y, Blumcke I, Su T, Choi J, Krishnan B, Murakami H, et al.
Neurology . 2022 Aug; 99(6):e616-e626. PMID: 35940890
Background And Objectives: We aim to provide detailed imaging-electroclinicopathologic characterization of the black line sign, a novel MRI marker for focal cortical dysplasia (FCD) IIB. Methods: 7T T2*-weighted gradient-echo (T2*w-GRE)...
9.
Choi J, Krishnan B, Hu S, Martinez D, Tang Y, Wang X, et al.
Epilepsia . 2022 Mar; 63(5):1225-1237. PMID: 35343593
Objective: We aimed to use a novel magnetic resonance fingerprinting (MRF) technique to examine in vivo tissue property characteristics of periventricular nodular heterotopia (PVNH). These characteristics were further correlated with...
10.
Zawar I, Krishnan B, Mackow M, Alexopoulos A, Nair D, Punia V
Epilepsia Open . 2021 Sep; 6(4):781-787. PMID: 34543516
Objectives: The gold standard for the management of drug-resistant focal epilepsy (DRE) is resection of epileptogenic zone. However, some patients may not be candidates for resection. Responsive neurostimulation is approved...