Balaji Manicassamy
Overview
Explore the profile of Balaji Manicassamy including associated specialties, affiliations and a list of published articles.
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Articles
70
Citations
4119
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Recent Articles
1.
Yang Q, Kelkar A, Manicassamy B, Neelamegham S
bioRxiv
. 2024 Sep;
PMID: 39282346
Besides acting as an immunological shield, the N-glycans of SARS-CoV-2 are also critical for viral life cycle. As the S2 subunit of spike is highly conserved across beta-coronaviruses, we determined...
2.
Du L, Deiter F, Bouzidi M, Billaud J, Simmons G, Dabral P, et al.
Commun Biol
. 2024 Apr;
7(1):486.
PMID: 38649430
The ongoing evolution of SARS-CoV-2 to evade vaccines and therapeutics underlines the need for innovative therapies with high genetic barriers to resistance. Therefore, there is pronounced interest in identifying new...
3.
Gaisina I, Li P, Du R, Cui Q, Dong M, Zhang C, et al.
Sci Adv
. 2024 Feb;
10(8):eadk9004.
PMID: 38394202
Seasonal or pandemic illness caused by influenza A viruses (IAVs) is a major public health concern due to the high morbidity and notable mortality. Although there are several approved drugs...
4.
Liang C, Huang I, Han J, Sownthirarajan B, Kulhankova K, Murray N, et al.
J Virol
. 2023 Oct;
97(11):e0090623.
PMID: 37843369
It is well known that influenza A viruses (IAV) initiate host cell infection by binding to sialic acid, a sugar molecule present at the ends of various sugar chains called...
5.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
mSphere
. 2023 Jan;
8(2):e0003423.
PMID: 36700653
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
6.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
mBio
. 2023 Jan;
14(1):e0018823.
PMID: 36700642
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
7.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
J Virol
. 2023 Jan;
97(2):e0008923.
PMID: 36700640
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
8.
Alqarni S, Cooper L, Achi J, Bott R, Sali V, Brown A, et al.
J Med Chem
. 2022 Oct;
65(20):14104-14120.
PMID: 36260129
The influenza A virus (IAV) is a highly contagious virus that causes pandemics and seasonal epidemics, which are major public health issues. Current anti-influenza therapeutics are limited partly due to...
9.
Zhao X, Lin X, Li P, Chen Z, Zhang C, Manicassamy B, et al.
PLoS Pathog
. 2022 Aug;
18(8):e1010756.
PMID: 35926068
Reporter viruses provide powerful tools for both basic and applied virology studies, however, the creation and exploitation of reporter influenza A viruses (IAVs) have been hindered by the limited tolerance...
10.
Malicoat J, Manivasagam S, Zuniga S, Sola I, McCabe D, Rong L, et al.
J Virol
. 2021 Dec;
96(3):e0183721.
PMID: 34851142
Research activities with infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are currently permitted only under biosafety level 3 (BSL3) containment. Here, we report the development of a single-cycle infectious...