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Bakheet E M Elsadek

Explore the profile of Bakheet E M Elsadek including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 136
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Recent Articles
1.
Aziz H, El-Saghier A, Badr M, Elsadek B, Abuo-Rahma G, Shoman M
Sci Rep . 2024 Oct; 14(1):24101. PMID: 39406816
A new group of thiazolidine-2,4-dione derivatives of ciprofloxacin having butyryl linker 3a-l was synthesized via an alkylation of thiazolidine-2,4-diones with butyryl ciprofloxacin with yield range 48-77% andfully characterized by various...
2.
Orabi M, Abouelela M, Darwish F, Abdelkader M, Elsadek B, Abdullah Al Awadh A, et al.
Front Pharmacol . 2024 Feb; 15:1337910. PMID: 38370475
Hepatocellular carcinoma (HCC) is a prevalent cancer worldwide. Late-stage detection, ineffective treatments, and tumor recurrence contribute to the low survival rate of the HCC. Conventional chemotherapeutic drugs, like doxorubicin (DOX),...
3.
Eisa M, Mansour A, Salama S, Elsadek B, Ashour A, Abdelghany T
Eur J Pharmacol . 2023 Dec; 960:176165. PMID: 38059444
Aim: Men are more susceptible to liver fibrosis (LF) than women. However, the underlying molecular mechanism, especially the role of estrogen/estrogen receptor (ER) activation in this sexual dimorphism is unclear....
4.
Abdel-Hamid M, Mansour A, Hassan M, Abdelhady R, Elsadek B, M El-Sayed E, et al.
Biol Pharm Bull . 2023 Nov; 46(11):1558-1568. PMID: 37914358
This study was designed to evaluate the potential protective impact of estrogen and estrogen receptor against diethylnitrosamine (DEN)-induced hepatocellular carcinoma (HCC) in rats. The levels of liver injury serum biomarkers,...
5.
Abuhamdah S, Saleem T, Elsadek B, Ashraf O, Hamdan A, El-Khateeb E, et al.
Int J Gen Med . 2022 Jul; 15:5795-5805. PMID: 35783999
Introduction: Traumatic spinal cord injury (TSCI) is a life-threatening neurological disorder and there is a lack of biomarker research, particularly human studies that could help to categorize the severity and...
6.
Hassan M, Abuhamdah S, Elsadek B, Abdelwahab A, Abd-Elhamid T, Fayed H, et al.
Clin Cosmet Investig Dermatol . 2022 Jun; 15:1073-1085. PMID: 35712358
Introduction: Verruca vulgaris is a benign hyperkeratotic proliferation of the epidermis. Few studies look at the differences in serum and tissue macrophage migration inhibitory factor (MIF) levels in verruca vulgaris,...
7.
Elsayed M, Aboelez M, Elsadek B, Sarhan H, Khaled K, Belal A, et al.
Pharmaceutics . 2022 Apr; 14(4). PMID: 35456714
Tolmetin sodium (TLM) is a non-steroidal anti-inflammatory drug (NSAIDs). TLM is used to treat inflammation, skeletal muscle injuries, and discomfort associated with bone disorders. Because of the delayed absorption from...
8.
Hassan M, Elsadek A, Mahmoud M, Elsadek B
Biochem Genet . 2021 Aug; 60(2):611-628. PMID: 34370118
Osteoarthritis (OA) etiology and pathogenesis not yet fully understood. We studied the role of vitamin D receptor single-nucleotide polymorphisms (VDR-SNPs), vitamin D3, serum and synovial macrophage migration inhibitory factor (MIF),...
9.
Elsadek B, Hassan M
Biochem Biophys Rep . 2021 Mar; 26:100966. PMID: 33718631
Several attempts have been made over the past decade to explore the concept of prodrug strategies that exploit PSA as a molecular target for the release of anticancer drugs in...
10.
Hassan M, Abuhamdah S, Abdel-Bary M, Wahman M, Abd-Elhamid T, Beshay M, et al.
Biosci Rep . 2020 Nov; 41(1). PMID: 33226065
Survivin is an inhibitor of apoptosis as well as a promoter of cell proliferation. Fibulin-3 is a matrix glycoprotein that displays potential for tumor suppression or propagation. The present study...