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Baiyu Chen

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Articles 70
Citations 727
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Recent Articles
1.
Cao J, Du T, He K, Dai Z, Xie X, Chen B, et al.
Arch Dermatol Res . 2025 Feb; 317(1):468. PMID: 39987260
IL-6 signaling is critical in the pathogenesis of several autoimmune diseases, including psoriasis and psoriatic arthritis. This study utilized Mendelian randomization (MR) analysis to investigate the genetic associations between IL-6...
2.
Chen B, Chen Z, He M, Zhang L, Yang L, Wei L
Front Immunol . 2025 Jan; 15:1525380. PMID: 39759531
Mesenchymal stem cells (MSCs), recognized for their self-renewal and multi-lineage differentiation capabilities, have garnered considerable wide attention since their discovery in bone marrow. Recent studies have underscored the potential of...
3.
Cao J, Du T, Li J, Chen B, Xie X, Zhang G, et al.
Front Immunol . 2024 Dec; 15:1464479. PMID: 39726598
Background: Lichen planus (LP), an autoimmune disorder, remains incompletely understood in terms of its etiological mechanisms. This study aims to elucidate causal relationships among immune cell populations, plasma metabolites, and...
4.
Lv L, Chen B, Gao Y, Sun N, Li W, Fu W
J Med Chem . 2024 Nov; 67(23):21400-21420. PMID: 39611350
Guided by the mode of action of , our previously discovered RORγt inverse agonist, we conducted five rounds of design syntheses and structure-activity relationship (SAR) studies, ultimately identifying RORγt inverse...
5.
Zhang X, Chen B, Zhou X, Chan S
Neural Netw . 2024 Aug; 179:106557. PMID: 39106566
Unsupervised semantic segmentation is important for understanding that each pixel belongs to known categories without annotation. Recent studies have demonstrated promising outcomes by employing a vision transformer backbone pre-trained on...
6.
Zeng Q, Wang Y, Javeed A, Chen F, Li J, Guan Y, et al.
Int J Biol Macromol . 2024 Feb; 263(Pt 2):130440. PMID: 38417763
To address the issue of food spoilage causing health and economic loss, we developed a pH/NH dual sensitive hydrogel based on polyvinyl alcohol/chitosan (PVA/CS) containing chitosan-phenol red (CP). The CP...
7.
Kessi M, Tang Y, Chen B, Wang G, Zhang C, He F, et al.
Pediatr Neurol . 2024 Feb; 153:137-143. PMID: 38382246
Background: Currently, there is no universally accepted standard treatment for ocular myasthenia gravis (OMG) in children. We aimed to investigate the possible proper regimens and timing of treatment for pediatric...
8.
Chen B, Pan Z, Mou M, Zhou Y, Fu W
Comput Biol Med . 2024 Jan; 169:107811. PMID: 38168647
Graph Neural Networks (GNNs) have gained significant traction in various sectors of AI-driven drug design. Over recent years, the integration of fragmentation concepts into GNNs has emerged as a potent...
9.
Kessi M, Chen B, Pang N, Yang L, Peng J, He F, et al.
Front Mol Neurosci . 2023 Aug; 16:1222321. PMID: 37555011
Background: Genotype-phenotype correlations of the -related neurodevelopmental disorders such as global developmental delay (GDD)/intellectual disability (ID), epileptic encephalopathy (EE), and autism spectrum disorder (ASD) are unknown. We aimed to summarize...
10.
Kessi M, Chen B, Pan L, Yang L, Yang L, Peng J, et al.
Front Mol Neurosci . 2023 Jul; 16:1209760. PMID: 37448958
Objective: To investigate the pathogenesis of three novel variants (p.E411D, p.V622G, and p.A272V) in causing neurodevelopmental disorders and arrhythmia. Methods: Several molecular experiments were carried out on transfected human embryonic...