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Bai Hui Chen

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Articles 56
Citations 481
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Recent Articles
1.
Fu Y, Zheng Y, Li Z, Huang X, Wang X, Cui M, et al.
Neurobiol Dis . 2025 Mar; :106873. PMID: 40089164
Reactive astrogliosis is a critical process in the development of ischemic stroke. However, the precise mechanism by which reactive astrogliosis changes the pathogenesis of ischemic stroke remains elusive. Sterile alpha...
2.
Xiong Y, Cui M, Li Z, Fu Y, Zheng Y, Yu Y, et al.
Int Immunopharmacol . 2023 Dec; 127:111379. PMID: 38141409
Microglial activation and autophagy play a critical role in the progression of ischemic stroke and contribute to the regulation of neuroinflammation. Unc-51-like kinase 1 (ULK1) is the primary autophagy kinase...
3.
Xiong Y, Fu Y, Li Z, Zheng Y, Cui M, Zhang C, et al.
ACS Chem Neurosci . 2023 May; 14(11):1992-2007. PMID: 37161270
Glial activation is involved in neuroinflammation and blood-brain barrier (BBB) damage, which plays a key role in ischemic stroke-induced neuronal damage; therefore, regulating glial activation is an important way to...
4.
Cui M, Fu Y, Li Z, Zheng Y, Yu Y, Zhang C, et al.
Exp Neurol . 2023 Jan; 362:114323. PMID: 36690057
In this study, we investigated the effect of neuregulin-1 (NRG1) on demyelination and neurological function in an ischemic stroke model, and further explored its neuroprotective mechanisms. Adult male ICR mice...
5.
Lee C, Ahn J, Chen B, Kim D, Sim H, Lee T, et al.
Mol Med Rep . 2021 Jul; 24(3). PMID: 34212986
Tumor necrosis factor (TNF)‑α and TNF receptor 1 (TNF‑R1) play diverse roles in modulating the neuronal damage induced by cerebral ischemia. The present study compared the time‑dependent changes of TNF‑α...
6.
Yoo Y, Kim D, Chen B, Sim H, Kim B, Lee J, et al.
Lab Anim Res . 2021 Mar; 37(1):11. PMID: 33676586
Background: Aging is one of major causes triggering neurophysiological changes in many brain substructures, including the hippocampus, which has a major role in learning and memory. Thioredoxin (Trx) is a...
7.
Chen B, Park J, Lee Y, Kang I, Kim D, Hwang I, et al.
Biomed Pharmacother . 2018 Sep; 108:687-697. PMID: 30245469
Vascular dementia affects cognition by damaging axons and myelin. Melatonin is pharmacologically associated with various neurological disorders. In this study, effects of melatonin on cognitive impairment and related mechanisms were...
8.
Ahn J, Chen B, Park J, Shin B, Lee T, Cho J, et al.
J Tissue Eng Regen Med . 2018 May; 12(7):1646-1657. PMID: 29763986
There is lack of researches on effects of intravenously injected mesenchymal stem cells (MSCs) against transient cerebral ischemia (TCI). We investigated the disruption of the neurovascular unit (NVU), which comprises...
9.
Lee T, Chen B, Lee J, Shin M, Cho J, Lee H, et al.
Mol Med Rep . 2018 Apr; 17(6):8161-8166. PMID: 29658594
Insulin‑like growth factor‑I (IGF‑I) is a multifunctional protein present in the central nervous system. A number of previous studies have revealed alterations in IGF‑I and its receptor (IGF‑IR) expression in...
10.
Chen B, Ahn J, Park J, Song M, Kim H, Lee T, et al.
Chem Biol Interact . 2018 Mar; 286:71-77. PMID: 29548728
Rufinamide is a novel antiepileptic drug and commonly used in the treatment of Lennox-Gastaut syndrome. In the present study, we investigated effects of rufinamide on cognitive function using passive avoidance...