Badithe T Ashok
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Explore the profile of Badithe T Ashok including associated specialties, affiliations and a list of published articles.
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11
Citations
131
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Recent Articles
1.
Shanmugam A, Suriano R, Goswami N, Chaudhuri D, Ashok B, Rajoria S, et al.
Cell Stress Chaperones
. 2010 Oct;
16(2):225-34.
PMID: 20953748
Heat shock proteins such as gp96 are immunogenic and are widely used as vaccines in immunotherapy of cancers. The present study focuses on the use of peptide mimotopes as immunotherapeutic...
2.
Suriano R, Chaudhuri D, Johnson R, Lambers E, Ashok B, Kishore R, et al.
Cancer Res
. 2008 Aug;
68(15):6038-42.
PMID: 18676823
Neovascularization is critical for tumor growth and development. The cellular mediators for this process are yet to be defined. We discovered that bone marrow-derived endothelial progenitor cells (BM-EPC), having the...
3.
Tadi K, Ashok B, Chen Y, Banerjee D, Wysocka-Skrzela B, Konopa J, et al.
Cancer Biol Ther
. 2007 Oct;
6(10):1632-7.
PMID: 17921700
Chemotherapy in prostate cancer (CaP) even as an adjunct has not been a success. In this communication, we report the pre-clinical efficacy of a nitroacridine derivative, C-1748 (9[2'-hydroxyethylamino]-4-methyl-1-nitroacridine) in CaP...
4.
Chaudhuri D, Orsulic S, Ashok B
Mol Cancer Ther
. 2007 Jan;
6(1):334-45.
PMID: 17237292
Epidemiologic studies show a correlation between increased consumption of fruits and vegetables with reduced risk of ovarian cancer. One major bioactive compound found in cruciferous vegetables, particularly broccoli, is sulforaphane,...
5.
Ashok B, Tadi K, Garikapaty V, Chen Y, Huang Q, Banerjee D, et al.
Anticancer Drugs
. 2006 Dec;
18(1):87-94.
PMID: 17159506
Nitroacridines are potent DNA-binding and cytotoxic agents in cancer cells, but could not be developed clinically due to high systemic toxicities. We are developing a 1-nitroacridine derivative, 9-(2'-hydroxyethylamino)-4-methyl-1-nitroacridine (C-1748), as...
6.
Garikapaty V, Ashok B, Tadi K, Mittelman A, Tiwari R
Biochem Biophys Res Commun
. 2005 Dec;
340(2):718-25.
PMID: 16380095
Epidemiological evidences suggest that the progression and promotion of prostate cancer (CaP) can be modulated by diet. Since all men die with prostate cancer rather than of the disease, it...
7.
Garikapaty V, Ashok B, Tadi K, Mittelman A, Tiwari R
Prostate
. 2005 Dec;
66(5):453-62.
PMID: 16353249
Background: Cruciferous vegetables have been found to have anti-prostate cancer effects. The active compounds mediating these effects include indoles such as indole-3-carbinol (I3C) and isothiocyanates. I3C is unstable having tissue...
8.
Tadi K, Chang Y, Ashok B, Chen Y, Moscatello A, Schaefer S, et al.
Biochem Biophys Res Commun
. 2005 Oct;
337(3):1019-25.
PMID: 16219298
Considerable epidemiological evidence exists to link thyroid disease with differing patterns of dietary consumption, in particular, cruciferous vegetables. We have been studying the anti-thyroid cancer (TCa) activity of indole-3-carbinol (I3C)...
9.
Suriano R, Ghosh S, Ashok B, Mittelman A, Chen Y, Banerjee A, et al.
Cancer Res
. 2005 Jul;
65(14):6466-75.
PMID: 16024652
Heat shock protein gp96 induces a tumor-specific protective immunity in a variety of experimental tumor models. Because the primary sequences of the glycoprotein, gp96 are identical between tumor and normal...
10.
Narayanan R, Tiwari P, Inoa D, Ashok B
Life Sci
. 2005 Jun;
77(18):2312-23.
PMID: 15950245
The anticancer effect of 1-nitro-9-hydroxyethylamino acridine (C-857), a compound belonging to the 1-nitroacridine class, has been well documented. Despite its therapeutic efficacy, the clinical development of C-857 has been impeded...