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Badal C Roy

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Articles 13
Citations 245
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Recent Articles
1.
Standing D, Arnold L, Dandawate P, Ottemann B, Snyder V, Ponnurangam S, et al.
Mol Carcinog . 2022 Oct; 62(2):145-159. PMID: 36218231
Doublecortin like kinase 1 (DCLK1) plays a crucial role in several cancers including colon and pancreatic adenocarcinomas. However, its role in squamous cell carcinoma (SCC) remains unknown. To this end,...
2.
Ahmed I, Yusuf K, Roy B, Stubbs J, Anant S, Attard T, et al.
Int J Mol Sci . 2022 Jan; 23(1). PMID: 35008767
Decreases in short-chain-fatty-acids (SCFAs) are linked to inflammatory bowel disease (IBD). Yet, the mechanisms through which SCFAs promote wound healing, orchestrated by intestinal stem cells, are poorly understood. We discovered...
3.
Yu W, Haque I, Venkatraman A, Menden H, Mabry S, Roy B, et al.
Cell Mol Gastroenterol Hepatol . 2021 Sep; 13(2):425-440. PMID: 34563711
Background & Aims: Single immunoglobulin interleukin-1-related receptor (SIGIRR) is a major inhibitor of Toll-like receptor signaling. Our laboratory identified a novel SIGIRR stop mutation (p.Y168X) in an infant who died...
4.
Roy B, Ahmed I, Stubbs J, Zhang J, Attard T, Septer S, et al.
Cell Death Discov . 2021 Aug; 7(1):200. PMID: 34341333
No abstract available.
5.
Roy B, Ahmed I, Stubbs J, Zhang J, Attard T, Septer S, et al.
Cell Death Discov . 2021 Jul; 7(1):169. PMID: 34226497
Alternative promoter usage generates long and short isoforms (DCLK1-L and DCLK1-S) of doublecortin-like kinase-1 (DCLK1). Tight control of Notch signaling is important to prevent and restitute inflammation in the intestine....
6.
Ahmed I, Roy B, Raach R, Owens S, Xia L, Anant S, et al.
PLoS One . 2018 Nov; 13(11):e0206701. PMID: 30383855
Intestinal mucus layer disruption and gut microflora modification in conjunction with tight junction (TJ) changes can increase colonic permeability that allows bacterial dissemination and intestinal and systemic disease. We showed...
7.
Iyer S, Ranjan A, Elias H, Parrales A, Sasaki H, Roy B, et al.
Nat Commun . 2016 Nov; 7:13561. PMID: 27886186
The ability of cancer cells to survive and grow in anchorage- and serum-independent conditions is well correlated with their aggressiveness. Here, using a human whole-genome shRNA library, we identify TMIGD3...
8.
Ahmed I, Roy B, Khan S, Septer S, Umar S
Microorganisms . 2016 Sep; 4(2). PMID: 27681914
Inflammatory Bowel Disease (IBD) is a multifactorial disorder that conceptually occurs as a result of altered immune responses to commensal and/or pathogenic gut microbes in individuals most susceptible to the...
9.
Ahmed I, Roy B, Subramaniam D, Ganie S, Kwatra D, Dixon D, et al.
Carcinogenesis . 2016 Jan; 37(4):385-96. PMID: 26785732
Phytochemicals modulate key cellular signaling pathways and have proven anticancer effects. Alcea rosea(AR; Hollyhock) is an ornamental plant with known anti-inflammatory properties. This study explored its role as an anticancer...
10.
Feng Y, Sakamoto N, Wu R, Liu J, Wiese A, Green M, et al.
PLoS Genet . 2015 Nov; 11(11):e1005638. PMID: 26528816
Adenomatous polyposis coli (APC) inactivating mutations are present in most human colorectal cancers and some other cancers. The APC protein regulates the β-catenin protein pool that functions as a co-activator...