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B Westermark

Explore the profile of B Westermark including associated specialties, affiliations and a list of published articles. Areas
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Articles 281
Citations 7566
Followers 0
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Recent Articles
1.
Heldin C, Lennartsson J, Westermark B
J Intern Med . 2017 Sep; 283(1):16-44. PMID: 28940884
Platelet-derived growth factor (PDGF) isoforms and their receptors have important roles during embryogenesis, particularly in the development of various mesenchymal cell types in different organs. In the adult, PDGF stimulates...
2.
Jernberg Wiklund H, Westermark B
J Intern Med . 2014 Jun; 276(1):2-4. PMID: 24943457
No abstract available.
3.
Savary K, Caglayan D, Caja L, Tzavlaki K, Bin Nayeem S, Bergstrom T, et al.
Oncogene . 2013 Mar; 32(47):5409-20. PMID: 23524585
Glioblastoma multiforme (GBM) is an aggressive brain malignancy characterized by high heterogeneity and invasiveness. It is increasingly accepted that the refractory feature of GBM to current therapies stems from the...
4.
Swartling F, Ferletta M, Kastemar M, Weiss W, Westermark B
Oncogene . 2009 Jun; 28(35):3121-31. PMID: 19543319
Earlier we used a glioma model to identify loci in the mouse genome, which were repeatedly targeted by platelet-derived growth factor (PDGF)-containing Moloney murine leukemia viruses. The gene Prkg2, encoding...
5.
Tchougounova E, Jiang Y, Brasater D, Lindberg N, Kastemar M, Asplund A, et al.
Oncogene . 2009 Feb; 28(12):1537-48. PMID: 19219070
SOX5 is a member of the high-mobility group superfamily of architectural non-histone proteins involved in gene regulation and maintenance of chromatin structure in a wide variety of developmental processes. Sox5...
6.
Tchougounova E, Kastemar M, Brasater D, Holland E, Westermark B, Uhrbom L
Oncogene . 2007 Apr; 26(43):6289-96. PMID: 17438529
In a subset of gliomas, the platelet-derived growth factor (PDGF) signaling pathway is perturbed. This is usually an early event occurring in low-grade tumors. In high-grade gliomas, the subsequent loss...
7.
El-Obeid A, Hesselager G, Westermark B, Nister M
Biochem Biophys Res Commun . 2002 Jan; 290(1):349-58. PMID: 11779176
The simultaneous presence of the EGFR and its ligand TGF-alpha in human tumor tissues suggests that autocrine TGF-alpha stimulation drives tumor growth. Here we show that autocrine TGF-alpha stimulation does...
8.
Andrae J, Bongcam-Rudloff E, Hansson I, Lendahl U, Westermark B, Nister M
Mech Dev . 2001 Aug; 107(1-2):181-5. PMID: 11520676
The intermediate filament glial fibrillary acidic protein (GFAP) constitutes the major cytoskeletal protein in astrocytes (J. Neuroimmunol. 8 (1985) 203) and is traditionally referred to as a specific marker for...
9.
Hellmen E, Moller M, Blankenstein M, Andersson L, Westermark B
Breast Cancer Res Treat . 2000 Aug; 61(3):197-210. PMID: 10965996
Mammary spindle-cell tumours and sarcomas seem to be restricted to dogs and humans. Two cell lines from spontaneous primary canine mammary spindle-cell tumours (CMT-U304 and CMT-U309) and two cell lines...
10.
Bergstrom J, Westermark B, Heldin N
Exp Cell Res . 2000 Aug; 259(1):293-9. PMID: 10942601
Overexpression of Met is a common finding in thyroid carcinomas. Recently, we reported on overexpression and ligand-independent constitutive activation of Met in anaplastic thyroid carcinoma cells. In the present study...