B W Segelke
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Explore the profile of B W Segelke including associated specialties, affiliations and a list of published articles.
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10
Citations
426
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Recent Articles
1.
Shelby M, Gilbile D, Grant T, Seuring C, Segelke B, He W, et al.
IUCrJ
. 2020 Jan;
7(Pt 1):30-41.
PMID: 31949902
For serial femtosecond crystallography at X-ray free-electron lasers, which entails collection of single-pulse diffraction patterns from a constantly refreshed supply of microcrystalline sample, delivery of the sample into the X-ray...
2.
Murillo A, Li H, Alber T, Baker E, Berger J, Cherney L, et al.
Infect Disord Drug Targets
. 2007 Nov;
7(2):127-39.
PMID: 17970224
Tuberculosis (TB) infects one-third of the world population. Despite 50 years of available drug treatments, TB continues to increase at a significant rate. The failure to control TB stems in...
3.
Coleman M, Lao V, Segelke B, Beernink P
J Proteome Res
. 2004 Oct;
3(5):1024-32.
PMID: 15473692
Protein expression screening methods are essential for proteomic scale characterization of gene and cDNA expression libraries. Screening methods are also important for the identification of highly expressed protein targets, for...
4.
Beernink P, Segelke B, Hadi M, Erzberger J, Wilson 3rd D, Rupp B
J Mol Biol
. 2001 Apr;
307(4):1023-34.
PMID: 11286553
The major human abasic endonuclease, Ape1, is an essential DNA repair enzyme that initiates the removal of apurinic/apyrimidinic sites from DNA, excises 3' replication-blocking moieties, and modulates the DNA binding...
5.
Dong J, Weisgraber K, Segelke B, Rupp B, Capila I, Hernaiz M, et al.
Biochemistry
. 2001 Mar;
40(9):2826-34.
PMID: 11258893
Apolipoprotein E (apoE) is an important lipid-transport protein in human plasma and brain. It has three common isoforms (apoE2, apoE3, and apoE4). ApoE is a major genetic risk factor in...
6.
Segelke B, Forstner M, Knapp M, Trakhanov S, Parkin S, Newhouse Y, et al.
Protein Sci
. 2000 Jun;
9(5):886-97.
PMID: 10850798
An amino-terminal fragment of human apolipoprotein E3 (residues 1-165) has been expressed and crystallized in three different crystal forms under similar crystallization conditions. One crystal form has nearly identical cell...
7.
Porcelli S, Segelke B, Sugita M, Wilson I, Brenner M
Immunol Today
. 1998 Aug;
19(8):362-8.
PMID: 9709504
No abstract available.
8.
Segelke B, Nguyen D, Chee R, Xuong N, Dennis E
J Mol Biol
. 1998 Jun;
279(1):223-32.
PMID: 9636712
Three crystal forms of Naja naja naja phospholipase A2 were discovered through random crystallization screening, including two heretofore uncharacterized forms. The crystallization conditions for both of these novel crystal forms...
9.
Zeng Z, Castano A, Segelke B, Stura E, Peterson P, Wilson I
Science
. 1997 Jul;
277(5324):339-45.
PMID: 9219685
CD1 represents a third lineage of antigen-presenting molecules that are distantly related to major histocompatibility complex (MHC) molecules in the immune system. The crystal structure of mouse CD1d1, corresponding to...
10.
Plesniak L, Boegeman S, Segelke B, Dennis E
Biochemistry
. 1993 May;
32(19):5009-16.
PMID: 8494876
Transferred NOE experiments have been carried out on cobra venom (Naja naja naja) phospholipase A2 (PLA2) with substrate analogues which serve as potent inhibitors. 1-(Hexylthio)-2-(hexanoylamino)-1,2-dideoxy-sn-glycero-3-pho sphoethanolamine (PE) and the corresponding...