B V V G Reddy
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Explore the profile of B V V G Reddy including associated specialties, affiliations and a list of published articles.
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9
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626
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Recent Articles
1.
Sun S, Reddy B, Irvine K
Nat Commun
. 2015 Oct;
6:8402.
PMID: 26420589
Hippo signalling controls organ growth and cell fate by regulating the activity of the kinase Warts. Multiple Hippo pathway components localize to apical junctions in epithelial cells, but the spatial...
2.
Reddy B, Irvine K
Dev Cell
. 2013 Mar;
24(5):459-71.
PMID: 23484853
EGFR and Hippo signaling pathways both control growth and, when dysregulated, contribute to tumorigenesis. We find that EGFR activates the Hippo pathway transcription factor Yorkie and demonstrate that Yorkie is...
3.
Reddy B, Irvine K
Development
. 2011 Nov;
138(23):5201-12.
PMID: 22069188
Glia perform diverse and essential roles in the nervous system, but the mechanisms that regulate glial cell numbers are not well understood. Here, we identify and characterize a requirement for...
4.
Rauskolb C, Pan G, Reddy B, Oh H, Irvine K
PLoS Biol
. 2011 Jun;
9(6):e1000624.
PMID: 21666802
The Hippo signaling pathway has a conserved role in growth control and is of fundamental importance during both normal development and oncogenesis. Despite rapid progress in recent years, key steps...
5.
Reddy B, Rauskolb C, Irvine K
Development
. 2010 Jun;
137(14):2397-408.
PMID: 20570939
The Drosophila optic lobe develops from neuroepithelial cells, which function as symmetrically dividing neural progenitors. We describe here a role for the Fat-Hippo pathway in controlling the growth and differentiation...
6.
Oh H, Reddy B, Irvine K
Dev Biol
. 2009 Sep;
335(1):188-97.
PMID: 19733165
The Fat-Hippo signaling pathway plays an important role in the regulation of normal organ growth during development, and in pathological growth during cancer. Fat-Hippo signaling controls growth through a transcriptional...
7.
Lin Y, Reddy B, Irvine K
Dev Dyn
. 2008 Nov;
237(12):3703-14.
PMID: 18985719
Mucin type O-glycosylation is a widespread modification of eukaryotic proteins, but its functional requirements remain incompletely understood. It is initiated by the attachment of N-acetylgalactosamine (GalNAc) to Ser or Thr...
8.
The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation
Reddy B, Irvine K
Development
. 2008 Aug;
135(17):2827-38.
PMID: 18697904
A cassette of cytoplasmic Drosophila tumor suppressors, including the kinases Hippo and Warts, has recently been linked to the transmembrane tumor suppressor Fat. These proteins act within interconnected signaling pathways,...
9.
Reddy B, Kalraiya R
Biochim Biophys Acta
. 2006 Jun;
1760(9):1393-402.
PMID: 16806716
B16BL6 cells, selected specifically for invasive characteristics from B16F10 mouse melanoma cells, displayed greater ability to metastasize to lungs and produced larger colonies than the parent cells, when injected intravenously....