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B Spinnewyn

Explore the profile of B Spinnewyn including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 197
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Recent Articles
1.
Chandrasekaran K, Mehrabian Z, Spinnewyn B, Chinopoulos C, Drieu K, Fiskum G
Pharmacopsychiatry . 2003 Sep; 36 Suppl 1:S89-94. PMID: 13130395
In this study, we compared the protective effect of bilobalide, a purified terpene lactone component of ginkgo biloba extract EGb 761, (definition see editorial) and EGb 761 against ischemic injury...
2.
Chandrasekaran K, Mehrabian Z, Spinnewyn B, Drieu K, Fiskum G
Brain Res . 2001 Dec; 922(2):282-92. PMID: 11743961
The neuroprotective effect of Ginkgo biloba extract (EGb 761) against ischemic injury has been demonstrated in animal models. In this study, we compared the protective effect of bilobalide, a purified...
3.
Marin J, Cornet S, Spinnewyn B, Auguet M, Chabrier P
Neuroreport . 2000 May; 11(6):1357-60. PMID: 10817621
Formation of the lipid peroxidation product 8-epi-prostaglandin2alpha (8-epi-PGF2alpha) a bioactive marker of oxidative stress, was quantified in in vitro and in vivo models of neuronal death. In culture media of...
4.
Chabrier P, Auguet M, Spinnewyn B, Auvin S, Cornet S, Marin J, et al.
Proc Natl Acad Sci U S A . 1999 Sep; 96(19):10824-9. PMID: 10485910
Nitric oxide (NO) and reactive oxygen species (ROS) act independently as well as cooperatively to induce neuronal death in acute neurological disorders. Inhibition of neuronal nitric oxide synthase (nNOS) and...
5.
Spinnewyn B, Cornet S, Auguet M, Chabrier P
J Cereb Blood Flow Metab . 1999 Feb; 19(2):139-43. PMID: 10027768
Both nitric oxide synthase (NOS) inhibitors and free radical scavengers have been shown to protect brain tissue in ischemia-reperfusion injury. Nitric oxide and superoxide anion act via distinct mechanisms and...
6.
Domingo M, Spinnewyn B, Chabrier P, Braquet P
Brain Res . 1994 Mar; 640(1-2):268-76. PMID: 8004455
This study investigated the distribution of platelet activating factor (PAF) binding sites in the brain and their involvement in global ischemia in a model of bilateral common carotid occlusion in...
7.
Duverger D, Spinnewyn B, Pirotzky E, Braquet P
Brain Res . 1991 Nov; 565(2):312-20. PMID: 1668814
Recent studies have demonstrated that measurement of peripheral type benzodiazepine binding sites (PTBBS) levels may be useful as an index for quantification of neuronal damage. In the present study, we...
8.
Braquet P, Spinnewyn B, Demerle C, Hosford D, Marcheselli V, Rossowska M, et al.
Ann N Y Acad Sci . 1989 Jan; 559:296-312. PMID: 2672941
No abstract available.
9.
Domingo M, Spinnewyn B, Chabrier P, Braquet P
Biochem Biophys Res Commun . 1988 Mar; 151(2):730-6. PMID: 2831903
The existence of specific binding sites for [3H]-labelled PAF ([3H]PAF) was investigated on membrane preparations of gerbil brain. Binding assays of [3H]PAF showed a specific, saturable, reversible and time dependent...
10.
Braquet P, Spinnewyn B, Blavet N, Marcheselli V, Rossawska M, Bazan N
Biomed Biochim Acta . 1988 Jan; 47(10-11):S195-218. PMID: 3073761
No abstract available.