B R Gibney
Overview
Explore the profile of B R Gibney including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
377
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Recent Articles
1.
Gibney B
Methods Enzymol
. 2016 Sep;
580:417-38.
PMID: 27586343
Complete thermodynamic descriptions of the interactions of cofactors with proteins via equilibrium studies are challenging, but are essential to the evaluation of designed metalloproteins. While decades of studies on protein-protein...
2.
Gibney B, Huang S, Skalicky J, Fuentes E, Wand A, Dutton P
Biochemistry
. 2001 Aug;
40(35):10550-61.
PMID: 11523997
We have investigated the properties of the two hemes bound to histidine in the H10 positions of the uniquely structured apo form of the heme binding four-helix bundle protein maquette...
3.
Kennedy M, Gibney B
Curr Opin Struct Biol
. 2001 Aug;
11(4):485-90.
PMID: 11495743
Metalloprotein and redox protein design are rapidly advancing toward the chemical synthesis of novel proteins that have predictable structures and functions. Current data demonstrate a breadth of successful approaches to...
4.
Kennedy M, Silchenko S, Houndonougbo N, Gibney B, Dutton P, Rodgers K, et al.
J Am Chem Soc
. 2001 Jul;
123(19):4635-6.
PMID: 11457264
No abstract available.
5.
Ugulava N, Gibney B, JARRETT J
Biochemistry
. 2001 Jul;
40(28):8343-51.
PMID: 11444981
Biotin synthase is an iron-sulfur protein that utilizes AdoMet to catalyze the presumed radical-mediated insertion of a sulfur atom between the saturated C6 and C9 carbons of dethiobiotin. Biotin synthase...
6.
Grosset A, Gibney B, Rabanal F, Moser C, Dutton P
Biochemistry
. 2001 May;
40(18):5474-87.
PMID: 11331012
New understanding of the engineering and allosteric regulation of natural protein conformational switches (such as those that couple chemical and ionic signals, mechanical force, and electro/chemical free energy for biochemical...
7.
Shifman J, Gibney B, Sharp R, Dutton P
Biochemistry
. 2000 Dec;
39(48):14813-21.
PMID: 11101297
The effects of various mechanisms of metalloporphyrin reduction potential modulation were investigated experimentally using a robust, well-characterized heme protein maquette, synthetic protein scaffold H10A24 [¿CH(3)()CONH-CGGGELWKL.HEELLKK.FEELLKL.AEERLKK. L-CONH(2)()¿(2)](2). Removal of the iron...
8.
Gibney B, Isogai Y, Rabanal F, Reddy K, Grosset A, Moser C, et al.
Biochemistry
. 2000 Sep;
39(36):11041-9.
PMID: 10998241
Heme A, a prosthetic group of cytochrome c oxidase [EC 1.9.3.1], has been introduced into two de novo designed four helix bundle proteins, [H10A24](2) and [H10H24](2), known to bind 2-4...
9.
Sharp R, Palmitessa A, Gibney B, Moser C, Dutton P
Biochem Soc Trans
. 2000 Aug;
27(4):572-6.
PMID: 10917644
No abstract available.
10.
Ugulava N, Gibney B, JARRETT J
Biochemistry
. 2000 May;
39(17):5206-14.
PMID: 10819988
Biotin synthase catalyzes the insertion of a sulfur atom into the saturated C6 and C9 carbons of dethiobiotin. This reaction has long been presumed to occur through radical chemistry, and...