Alpha 2.0
Login Register
» Authors » B Opalka

B Opalka

Explore the profile of B Opalka including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 68
Citations 309
Followers 0
Related Specialties
Hematology
Oncology
Genetics
Top 10 Co-Authors
S Seeber
O Kloke
N Niederle
R Becher
T Moritz
J Schutte
W Bardenheuer
U W Schaefer
U B Wandl
D W Beelen
Published In
Blood
Br J Haematol
Bone Marrow Transplant
Leukemia
Leuk Res
Affiliations
Soon will be listed here.
Recent Articles
1.
Differential expression of drug-resistance-related genes between sensitive and resistant blasts in acute myeloid leukemia
Eisele L, Klein-Hitpass L, Chatzimanolis N, Opalka B, Boes T, Seeber S, et al.
Acta Haematol . 2006 Nov; 117(1):8-15. PMID: 17095854
Drug resistance constitutes a considerable problem in the therapy of acute myeloid leukemia (AML). In order to identify genes which might be related to drug resistance, we retrospectively studied gene...
2.
Cellular in vitro immune function in multiple myeloma patients after high-dose chemotherapy and autologous peripheral stem cell transplantation
Lindemann M, Schuett P, Moritz T, Ottinger H, Opalka B, Seeber S, et al.
Leukemia . 2005 Jan; 19(3):490-2. PMID: 15674357
No abstract available.
3.
Thalidomide in combination with vincristine, epirubicin and dexamethasone (VED) for previously untreated patients with multiple myeloma
Schutt P, Ebeling P, Buttkereit U, Brandhorst D, Opalka B, Hoiczyk M, et al.
Eur J Haematol . 2004 Dec; 74(1):40-6. PMID: 15613105
The present study aimed to evaluate the side-effects and efficacy of thalidomide in combination with an anthracycline-containing chemotherapy regimen in previously untreated myeloma patients. Thalidomide (400 mg/d) was combined with...
4.
A comparison of chimerism and minimal residual disease between four different allogeneic transplantation methods in patients with chronic myelogenous leukemia in first chronic phase
Elmaagacli A, Runkel K, Steckel N, Opalka B, Trenschel R, Seeber S, et al.
Bone Marrow Transplant . 2001 Jul; 27(8):809-15. PMID: 11477437
The detection of chimerism, residual molecular and cytogenetic disease following transplantation of peripheral blood stem cells (PBSCT) with a nonmyeloablative conditioning (n = 9) and the transplantation of highly purified...
5.
Estimating the relapse stage in chronic myeloid leukaemia patients after allogeneic stem cell transplantation by the amount of BCR-ABL fusion transcripts detected using a new real-time polymerase chain reaction method
Elmaagacli A, Freist A, Hahn M, Opalka B, Seeber S, Schaefer U, et al.
Br J Haematol . 2001 Jul; 113(4):1072-5. PMID: 11442504
We have used a new single-step real-time reverse transcription polymerase chain reaction (RT-PCR) method to quantify BCR-ABL transcripts, thereby estimating the relapse stage in chronic myeloid leukaemia patients after allogeneic...
6.
Transplantation of highly purified HLA-identical sibling donor peripheral blood CD34+ cells without prophylactic post-transplant immunosuppression in adult patients with first chronic phase chronic myeloid leukemia: results of a phase II study
Beelen D, Peceny R, Elmaagacli A, Ottinger H, Kummer G, Opalka B, et al.
Bone Marrow Transplant . 2000 Nov; 26(8):823-9. PMID: 11081380
The feasibility of transplantation using highly purified G-CSF-mobilized peripheral blood CD34+ cells from HLA-identical sibling donors without prophylactic post-transplant immunosuppression was prospectively studied in 10 adult first chronic phase chronic...
7.
The amount of BCR-ABL fusion transcripts detected by the real-time quantitative polymerase chain reaction method in patients with Philadelphia chromosome positive chronic myeloid leukemia correlates with the disease stage
Elmaagacli A, Beelen D, Opalka B, Seeber S, Schaefer U
Ann Hematol . 2000 Sep; 79(8):424-31. PMID: 10985361
The use of the real-time reverse-transcription polymerase-chain reaction (RT-PCR) method to quantify BCR-ABL transcripts before and after allogeneic transplant was prospectively studied in 65 patients with chronic myeloid leukemia (CML)....
8.
Type and position of promoter elements in retroviral vectors have substantial effects on the expression level of an enhanced green fluorescent protein reporter gene
Flasshove M, Bardenheuer W, Schneider A, Hirsch G, Bach P, Bury C, et al.
J Cancer Res Clin Oncol . 2000 Aug; 126(7):391-9. PMID: 10929761
Purpose: Although gene transfer with retroviral vectors has already been applied to patients as part of clinical protocols, low expression of transgenes in target cells still remains a problem. Therefore,...
9.
E1A overcomes the apoptosis block in BCR-ABL+ leukemia cells and renders cells susceptible to induction of apoptosis by chemotherapeutic agents
Stiewe T, Parssanedjad K, Esche H, Opalka B, Putzer B
Cancer Res . 2000 Aug; 60(14):3957-64. PMID: 10919674
A crucial function of the BCR-ABL chimeric gene in chronic myeloid leukemia is the prolongation of cell survival by inhibition of apoptosis. BCR-ABL expression confers cross-resistance to multiple genotoxic anticancer...
10.
Transformation-defective adenovirus 5 E1A mutants exhibit antioncogenic properties in human BLM melanoma cells
Dickopp A, Esche H, Swart G, Seeber S, Kirch H, Opalka B
Cancer Gene Ther . 2000 Aug; 7(7):1043-50. PMID: 10917207
Adenoviral E1 A proteins exhibit a strong tumor-suppressive activity in human tumor cells. However, E1 A is capable of transforming rodent and human cells in cooperation with other oncoproteins, such...