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B Labedan

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Recent Articles
1.
Lespinet O, Labedan B
Cell Mol Life Sci . 2006 Feb; 63(5):517-23. PMID: 16465439
Despite the current availability of several hundreds of thousands of amino acid sequences, more than 39% of the well-defined enzyme activities (EC numbers) are not associated with any sequence in...
2.
Perriere G, Bessieres P, Labedan B
Nucleic Acids Res . 1999 Dec; 28(1):68-71. PMID: 10592183
As the number of complete microbial genomes publicly available is still growing, the problem of annotation quality in these very large sequences remains unsolved. Indeed, the number of annotations associated...
3.
Labedan B, Boyen A, Baetens M, Charlier D, Chen P, Cunin R, et al.
J Mol Evol . 1999 Sep; 49(4):461-73. PMID: 10486004
Forty-four sequences of ornithine carbamoyltransferases (OTCases) and 33 sequences of aspartate carbamoyltransferases (ATCases) representing the three domains of life were multiply aligned and a phylogenetic tree was inferred from this...
4.
Perriere G, Bessieres P, Labedan B
Nucleic Acids Res . 1998 Dec; 27(1):63-5. PMID: 9847143
Since the obtention of the complete sequence of Haemophilus influenzae Rd in 1995, the number of bacterial genomes entirely sequenced has regularly increased. A problem is that the quality of...
5.
Gerard E, Labedan B, Forterre P
Gene . 1998 Nov; 222(1):99-106. PMID: 9813262
The region upstream of the dinF-like gene of the hyperthermophilic archaeon Pyrococcus strain AL585 has been cloned and sequenced. This region contains an open reading frame (ORF) that encodes a...
6.
De Rosa R, Labedan B
Mol Biol Evol . 1998 Mar; 15(1):17-27. PMID: 9491601
We have tried to approach the nature of the last common ancestor to Haemophilus influenzae and Escherichia coli and to determine how each bacterium could have diverged from this putative...
7.
Riley M, Labedan B
J Mol Biol . 1997 May; 268(5):857-68. PMID: 9180377
Paralogous genes are genes which descend from a progenitor gene which has duplicated as an ancestral gene, each copy having diverged prior to speciation. With comprehensive information available on functions...
8.
Kort R, Liebl W, Labedan B, Forterre P, Eggen R, de Vos W
Extremophiles . 1997 Feb; 1(1):52-60. PMID: 9680336
The hyperthermophilic bacterium Thermotoga maritima, which grows at up to 90 degrees C, contains an L-glutamate dehydrogenase (GDH). Activity of this enzyme could be detected in T. maritima crude extracts,...
9.
Guipaud O, Labedan B, Forterre P
Gene . 1996 Sep; 174(1):121-8. PMID: 8863738
We have cloned and sequenced two overlapping DNA fragments (3236 bp) containing a gene encoding the ATPase subunit of a type II DNA topoisomerase from the hyperthermophilic bacterion Thermotoga maritima...
10.
Bouyoub A, Barbier G, Forterre P, Labedan B
J Mol Biol . 1996 Aug; 261(2):144-54. PMID: 8757283
The first example of a hyperthermophilic adenylosuccinate synthetase is reported, which is an enzyme that must maintain its folded structure at temperatures as high as 102 degrees C. The amino...