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B K Taylor

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Articles 39
Citations 634
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Recent Articles
1.
Cooper A, Nie A, Hedden N, Herzog H, Taylor B
bioRxiv . 2025 Feb; PMID: 39975116
Nerve damage induces a robust expression of the pain-modulatory peptide neuropeptide Y (NPY) in large-diameter primary afferent neurons that innervate the dorsal horn of the spinal cord and the dorsal...
2.
Santos D, Donahue R, Laird D, Oliveira M, Taylor B
Neuropharmacology . 2021 Dec; 205:108907. PMID: 34856203
Pioglitazone, an agonist at peroxisome proliferator-activated receptor gamma, is FDA-approved for the treatment of insulin resistance in type 2 diabetes. Numerous studies in male rodents suggest that pioglitazone inhibits inflammatory...
3.
Kaushal R, Taylor B, Jamal A, Zhang L, Ma F, Donahue R, et al.
Neuroscience . 2016 Aug; 334:148-159. PMID: 27520081
Trigeminal neuropathic pain is described as constant excruciating facial pain. The study goal was to investigate the role of nucleus locus coeruleus (LC) in a model of chronic orofacial neuropathic...
4.
Iannitti T, Kerr B, Taylor B
Curr Top Behav Neurosci . 2014 Mar; 20:75-97. PMID: 24590824
The neuropathic pain of multiple sclerosis is quite prevalent and severely impacts quality of life. A few randomized, placebo-controlled, blinded clinical trials suggest that cannabis- and anticonvulsant-based treatments provide partial...
5.
Taylor B, Fu W, Kuphal K, Stiller C, Winter M, Chen W, et al.
Neuroscience . 2013 Nov; 256:178-94. PMID: 24184981
Neuropeptide Y (NPY) is present in the superficial laminae of the dorsal horn and inhibits spinal nociceptive processing, but the mechanisms underlying its anti-hyperalgesic actions are unclear. We hypothesized that...
6.
Corder G, Doolen S, Donahue R, Winter M, Jutras B, He Y, et al.
Science . 2013 Sep; 341(6152):1394-9. PMID: 24052307
Opioid receptor antagonists increase hyperalgesia in humans and animals, which indicates that endogenous activation of opioid receptors provides relief from acute pain; however, the mechanisms of long-term opioid inhibition of...
7.
Morgenweck J, Griggs R, Donahue R, Zadina J, Taylor B
Neuropharmacology . 2013 Feb; 70:236-46. PMID: 23415633
Peroxisome proliferator-activated receptor gamma (PPARγ) is emerging as a new pharmacotherapeutic target for chronic pain. When oral (3-30 mg/kg/day in chow for 7 wk) or twice-daily intraperitoneal (1-10 mg/kg/day for...
8.
Morgenweck J, Abdel-Aleem O, McNamara K, Donahue R, Badr M, Taylor B
Neuropharmacology . 2009 Nov; 58(2):337-45. PMID: 19891980
Systemic administration of thiazolidinediones reduces peripheral inflammation in vivo, presumably by acting at peroxisome proliferator-activated receptor gamma (PPARgamma) in peripheral tissues. Based on a rapidly growing body of literature indicating...
9.
Intondi A, Zadina J, Zhang X, Taylor B
Neuroscience . 2009 Nov; 165(3):914-22. PMID: 19879928
We used a new computer-assisted method to precisely localize and efficiently quantify increases in neuropeptide Y immunoreactivity (NPY-ir) along the mediolateral axis of the L4 dorsal horn (DH) following transection...
10.
Brightwell J, Taylor B
Neuroscience . 2009 Feb; 160(1):174-85. PMID: 19223010
Current theories of neuropathic hypersensitivity include an imbalance of supraspinal inhibition and facilitation. Our overall hypothesis is that the locus coeruleus (LC), classically interpreted as a source of pain inhibition,...