B Gooptu
Overview
Explore the profile of B Gooptu including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
278
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0
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Recent Articles
1.
Gooptu B, Ekeowa U, Lomas D
Eur Respir J
. 2009 Aug;
34(2):475-88.
PMID: 19648523
The severe, early onset emphysema that occurs in patients with circulating deficiency of alpha(1)-antitrypsin (alpha(1)-AT) attests to the importance of this protease inhibitor in maintaining lung parenchymal integrity. It has...
2.
Gooptu B, Ward L, Ansari S, Eraut C, Law D, Davison A
Emerg Med J
. 2006 Jul;
23(8):636-8.
PMID: 16858099
Background: Appropriate resuscitation of hypoxic patients is fundamental in emergency admissions. To achieve this, it is standard practice of ambulance staff to administer high concentrations of oxygen to patients who...
3.
Gooptu B, Hazes B, Chang W, Dafforn T, Carrell R, Read R, et al.
Proc Natl Acad Sci U S A
. 2000 Jan;
97(1):67-72.
PMID: 10618372
The serpins are a family of proteinase inhibitors that play a central role in the control of proteolytic cascades. Their inhibitory mechanism depends on the intramolecular insertion of the reactive...
4.
Davis R, Shrimpton A, Holohan P, Bradshaw C, Feiglin D, Collins G, et al.
Nature
. 1999 Oct;
401(6751):376-9.
PMID: 10517635
Aberrant protein processing with tissue deposition is associated with many common neurodegenerative disorders; however, the complex interplay of genetic and environmental factors has made it difficult to decipher the sequence...
5.
Carrell R, Gooptu B
Curr Opin Struct Biol
. 1999 Jan;
8(6):799-809.
PMID: 9914261
Some of the most perplexing disorders in medicine are each now known to arise from the conformational instability of an underlying protein. The consequence is a continuum of pathologies with...