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B Gereben

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Articles 14
Citations 338
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Recent Articles
1.
Mohacsik P, Fuzesi T, Doleschall M, Szilvasy-Szabo A, Vancamp P, Hadadi E, et al.
Endocrinology . 2016 Jan; 157(3):1211-21. PMID: 26779746
The hypothalamic-pituitary-thyroid axis is governed by hypophysiotropic TRH-synthesizing neurons located in the hypothalamic paraventricular nucleus under control of the negative feedback of thyroid hormones. The mechanisms underlying the ontogeny of...
2.
Jansen S, Akintola A, Roelfsema F, van der Spoel E, M Cobbaert C, Ballieux B, et al.
Sci Rep . 2015 Jun; 5:11525. PMID: 26089239
Few studies have included subjects with the propensity to reach old age in good health, with the aim to disentangle mechanisms contributing to staying healthier for longer. The hypothalamic-pituitary-thyroid (HPT)...
3.
Schele E, Fekete C, Egri P, Fuzesi T, Palkovits M, Keller E, et al.
J Neuroendocrinol . 2012 Feb; 24(6):930-43. PMID: 22295972
Interleukin (IL)-6 deficient mice develop mature-onset obesity. Furthermore, i.c.v. administration of IL-6 increases energy expenditure, suggesting that IL-6 centrally regulates energy homeostasis. To investigate whether it would be possible for...
4.
Gereben B, Zeold A, Dentice M, Salvatore D, Bianco A
Cell Mol Life Sci . 2007 Nov; 65(4):570-90. PMID: 17989921
The thyroid hormone plays a fundamental role in the development, growth, and metabolic homeostasis in all vertebrates by affecting the expression of different sets of genes. A group of thioredoxin...
5.
Geyten S, Segers I, Gereben B, Bartha T, Rudas P, Larsen P, et al.
Mol Cell Endocrinol . 2001 Oct; 183(1-2):1-9. PMID: 11604218
A single dose of chicken growth hormone (cGH) or dexamethasone acutely increases circulating T(3) levels in 18-day-old chicken embryos through a reduction of hepatic type III iodothyronine deiodinase (D3). The...
6.
Vianna C, Hagen T, Zhang C, BACHMAN E, Boss O, Gereben B, et al.
Physiol Genomics . 2001 Apr; 5(3):137-45. PMID: 11285367
The cDNA of an uncoupling protein (UCP) homolog has been cloned from the swallow-tailed hummingbird, Eupetomena macroura. The hummingbird uncoupling protein (HmUCP) cDNA was amplified from pectoral muscle (flight muscle)...
7.
Gereben B, Salvatore D, Harney J, Tu H, Larsen P
Mol Endocrinol . 2001 Jan; 15(1):112-24. PMID: 11145743
Types 1 and 2 iodothyronine deiodinases (D1 and D2) catalyze the production of T(3) from T(4). D2 mRNA is abundant in the human thyroid but very low in adult rat...
8.
Baqui M, Gereben B, Harney J, Larsen P, Bianco A
Endocrinology . 2000 Nov; 141(11):4309-12. PMID: 11089566
We compared the subcellular localization of FLAG-epitope tagged Types 1 and 2 deiodinases (D1 and D2) transiently expressed in human embryonic kidney (HEK-293) and mouse neuroblastoma (NB2A) cells. D2 is...
9.
Gereben B, Goncalves C, Harney J, Larsen P, Bianco A
Mol Endocrinol . 2000 Nov; 14(11):1697-708. PMID: 11075806
We investigated the mechanism by which T4 regulates its activation to T3 by the type 2 iodothyronine deiodinase (D2). D2 is a short- lived (t1/2 50 min), 31-kDa endoplasmic reticulum...
10.
Bartha T, Kim S, Salvatore D, Gereben B, Tu H, Harney J, et al.
Endocrinology . 1999 Dec; 141(1):229-37. PMID: 10614643
The type 2 iodothyronine deiodinase (D2) catalyzes T4 activation. In humans, unlike rodents, it is widely expressed, and its action probably contributes to both intracellular and plasma T3 pools. We...