B Fermini
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Explore the profile of B Fermini including associated specialties, affiliations and a list of published articles.
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28
Citations
664
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Recent Articles
1.
Alexandrou A, Milnes J, Sun S, Fermini B, Kim S, Jenkinson S, et al.
J Physiol Pharmacol
. 2014 Sep;
65(4):511-23.
PMID: 25179083
Diverse non-cardiac drugs adversely influence cardiac electrophysiology by inhibiting repolarising K(+) currents mediated by channels encoded by the human ether-a-go-go-related gene (hERG). In this study, pharmacological blockade of hERG K(+)...
2.
Salata J, Jurkiewicz N, Jow B, Folander K, Guinosso Jr P, Raynor B, et al.
Am J Physiol
. 1996 Dec;
271(6 Pt 2):H2477-89.
PMID: 8997308
The delayed rectifier K+ current (IK) in rabbit heart has long been thought to consist of only a single, rapidly activating, dofetilide-sensitive current, IKr. However, we find that IK of...
3.
Jurkiewicz N, Wang J, Fermini B, Sanguinetti M, Salata J
Circulation
. 1996 Dec;
94(11):2938-46.
PMID: 8941124
Background: The class III antiarrhythmic agent RP 58866 and its active enantiomer, terikalant, are reported to selectively block the inward rectifier K+ current, IK1. These drugs have demonstrated efficacy in...
4.
Feng J, Li G, Fermini B, Nattel S
Am J Physiol
. 1996 May;
270(5 Pt 2):H1676-86.
PMID: 8928874
Cultured cell systems are valuable for the study of regulation of phenotypic expression, but little is known about the electrophysiological properties of human cardiac tissues in culture. The present studies...
5.
Li G, Feng J, Wang Z, Fermini B, Nattel S
Circ Res
. 1996 May;
78(5):903-15.
PMID: 8620611
The ultrarapid delayed rectifier K+ current (IKur) in human atrial cells appears to correspond to Kv1.5 cloned channels and to play an important role in human atrial repolarization. Kv1.5 channels...
6.
Li G, Feng J, Wang Z, Fermini B, Nattel S
Am J Physiol
. 1995 Aug;
269(2 Pt 2):H463-72.
PMID: 7653610
The cardiac transient outward current (Ito) has been shown in several species to consist of two components: 1) a 4-aminopyridine (4-AP)-sensitive component (Ito1) and 2) a 4-AP-resistant component (Ito2). In...
7.
Duan D, Fermini B, Nattel S
Circ Res
. 1995 Aug;
77(2):379-93.
PMID: 7542183
alpha-Adrenergic stimulation is known to play a role in cardiac arrhythmogenesis and to modulate a variety of cardiac K+ currents. The effects of alpha-adrenergic stimulation on Cl- currents are largely...
8.
Fermini B, Jurkiewicz N, Jow B, Guinosso Jr P, Baskin E, Lynch Jr J, et al.
J Cardiovasc Pharmacol
. 1995 Aug;
26(2):259-71.
PMID: 7475051
We studied the effects of NE-10064 (azimilide), a new antiarrhythmic agent reported to be a selective blocker of the slowly activating component of the delayed rectifier, IKs. In ferret papillary...
9.
Rampe D, Wang Z, Fermini B, Wible B, Dage R, Nattel S
J Pharmacol Exp Ther
. 1995 Jul;
274(1):444-9.
PMID: 7616429
Perhexiline maleate is an antianginal drug that has been shown to have antiarrhythmic effects in humans. To examine whether some of these clinical observations could be caused by block of...
10.
Wang Z, Fermini B, Feng J, Nattel S
Am J Physiol
. 1995 May;
268(5 Pt 2):H1992-2002.
PMID: 7771549
Rabbit atrial cells manifest a prominent transient outward K+ current (Ito1), but this current recovers slowly from inactivation and is unlikely to be important at physiological rates (3-5 Hz). Depolarization...