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B Edde

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Articles 29
Citations 869
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11.
Audebert S, Koulakoff A, Gros F, Denoulet P, Edde B
J Cell Sci . 1994 Aug; 107 ( Pt 8):2313-22. PMID: 7527057
Polyglutamylation is an important posttranslational modification of tubulin that is very active in nerve cells, where it accounts for the main factor responsible for tubulin heterogeneity. In the present work,...
12.
FOUQUET J, Edde B, Kann M, Wolff A, Desbruyeres E, Denoulet P
Cell Motil Cytoskeleton . 1994 Jan; 27(1):49-58. PMID: 7910783
The distribution of glutamylated tubulin has been analyzed in mammalian testis using the specific mAb GT335 by immunoelectron microscopy and immunoblotting. In spermatozoa of various species, immunogold labeling showed the...
13.
Audebert S, Desbruyeres E, Gruszczynski C, Koulakoff A, Gros F, Denoulet P, et al.
Mol Biol Cell . 1993 Jun; 4(6):615-26. PMID: 8104053
The relationship between microtubule dynamics and polyglutamylation of tubulin was investigated in young differentiating mouse brain neurons. Selective posttranslational labeling with [3H]glutamate and immunoblotting with a specific monoclonal antibody (GT335)...
14.
Wolff A, de Nechaud B, Chillet D, Mazarguil H, Desbruyeres E, Audebert S, et al.
Eur J Cell Biol . 1992 Dec; 59(2):425-32. PMID: 1493808
A monoclonal antibody (GT335) directed against polyglutamylated tubulin was obtained by immunization with a synthetic peptide which mimics the structure of the polyglutamylated site of alpha-tubulin. This peptide corresponds to...
15.
Edde B, Rossier J, Le Caer J, Prome J, Desbruyeres E, Gros F, et al.
Biochemistry . 1992 Jan; 31(2):403-10. PMID: 1370628
We have previously identified a major modification of neuronal alpha-tubulin which consists of the posttranslational addition of a varying number of glutamyl units on the gamma-carboxyl group of glutamate residue...
16.
Edde B, Denoulet P, Van Dorsselaer A, Mazarguil H, Le Caer J, Wehland J, et al.
Biochemistry . 1991 Oct; 30(43):10523-8. PMID: 1931974
Brain tubulin preparations contain an abundant type of tubulin which does not undergo the normal cycle of tyrosination-detyrosination, and whose nature is still unknown. We have used peptide sequence analysis...
17.
Edde B, Rossier J, Le Caer J, Koulakoff A, Gros F, Denoulet P
J Cell Biochem . 1991 Jun; 46(2):134-42. PMID: 1680872
We describe the presence of alpha-tubulin and MAP2 acetyltransferase activities in mouse brain. The enzyme(s) copurified with microtubules through two cycles of assembly-disassembly. Incubation of microtubule proteins with [3H]acetyl CoA...
18.
Edde B, Rossier J, Le Caer J, Desbruyeres E, Gros F, Denoulet P
Science . 1990 Jan; 247(4938):83-5. PMID: 1967194
The high degree of tubulin heterogeneity in neurons is controlled mainly at the posttranslational level. Several variants of alpha-tubulin can be posttranslationally labeled after incubation of cells with [3H]acetate or...
19.
Lockerbie R, Edde B, Prochiantz A
J Neurochem . 1989 Mar; 52(3):786-96. PMID: 2537377
We have shown recently that neuronal growth cones isolated from developing rat forebrain possess an appreciable activity of adenylate cyclase, which produces cyclic AMP and can be stimulated by various...
20.
Edde B, Denoulet P, de Nechaud B, Koulakoff A, Gros F
Biol Cell . 1989 Jan; 65(2):109-17. PMID: 2736326
Posttranslational modifications of tubulin were analyzed in mouse brain neurons and glia developing in culture. Purified tubulin was resolved by isoelectric focusing. After 3 weeks of culture, neurons were shown...