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B Brotman

Explore the profile of B Brotman including associated specialties, affiliations and a list of published articles. Areas
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Articles 77
Citations 794
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Recent Articles
1.
Prince A, Brotman B
Methods Mol Med . 2011 Mar; 29:65-70. PMID: 21374309
Chimpanzees, because of their near-human nature, have special needs that must be met by those who carry out medical research with them. Perhaps the most important of these is the...
2.
Prince A, Pawlotsky J, Soulier A, Tobler L, Brotman B, Pfahler W, et al.
J Viral Hepat . 2004 May; 11(3):236-42. PMID: 15117325
The availability of molecular beacon-based, real time polymerase chain reaction (PCR) and a semi-automated sample extraction procedure have made it possible for us to retrospectively examine HCV replication kinetics in...
3.
Shata M, Anthony D, Carlson N, Andrus L, Brotman B, Tricoche N, et al.
J Viral Hepat . 2002 Nov; 9(6):400-10. PMID: 12431201
The immune response to hepatitis C virus (HCV) is believed to be critical in determining the outcome of the disease. In this study we have analysed epitope recognition, cytokine profile,...
4.
Prince A, Brotman B
ILAR J . 2001 Jun; 42(2):85-8. PMID: 11406710
Chimpanzees have been shown to be exquisitely susceptible to human hepatitis viruses, without themselves developing clinical illness, thus providing an important model for studies on these agents. Chimpanzees have contributed...
5.
Prince A, Lee D, Brotman B
Transfusion . 2001 Mar; 41(3):329-32. PMID: 11274585
Background: Numerous reports have noted the existence of sera, particularly from resolving cases of HBV infection, that are positive for HBV DNA by PCR, despite being negative for HBsAg and...
6.
Pancholi P, Lee D, Liu Q, Tackney C, Taylor P, Perkus M, et al.
Hepatology . 2001 Feb; 33(2):448-54. PMID: 11172348
There are about 200 million chronic hepatitis B virus (HBV) carriers at high risk of development of cirrhosis and hepatocellular carcinoma. Termination of the carrier state may avert these risks....
7.
Takahashi K, Brotman B, Usuda S, Mishiro S, Prince A
Virology . 2000 Jan; 267(1):58-64. PMID: 10648183
Hepatitis B virus (HBV) belongs to the genus Orthohepadnavirus of the family Hepadnaviridae. Having been found in various animals (duck, heron, woodchuck, ground squirrel, and primates), hepadnaviruses must have undergone...
8.
Prince A, Brotman B, Lee D, Ren L, Moore B, Scheffel J
J Infect Dis . 1999 Sep; 180(4):987-91. PMID: 10479122
To determine whether there was a correlation between the kinetics or frequency of antibody to mammalian-derived hepatitis C virus (HCV) second envelope protein (E2) and development of chronicity or self-limitation...
9.
Prince A, Allan J, Andrus L, Brotman B, Eichber J, Fouts R, et al.
Science . 1999 Mar; 283(5405):1117-8. PMID: 10075569
No abstract available.
10.
Cohard M, Liu Q, Perkus M, Gordon E, Brotman B, Prince A
J Immunol Methods . 1998 Aug; 214(1-2):121-9. PMID: 9692864
The aim of this study was to evaluate HCV-cytotoxic T lymphocyte response from PBMC in bulk CTL assays and in CTL precursor analyses using in vitro stimulation with canarypox virus...