B Alessandri
Overview
Explore the profile of B Alessandri including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
322
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Recent Articles
1.
Inui T, Alessandri B, Heimann A, Nishimura F, Frauenknecht K, Sommer C, et al.
Neuroscience
. 2013 Mar;
242:1-10.
PMID: 23523747
Objective: Glutamate transporter-1 (GLT-1) maintains low concentrations of extracellular glutamate by removing glutamate from the extracellular space. It is controversial, however, whether upregulation of GLT-1 is neuroprotective under all ischemic/hypoxic...
2.
Rahimi Nedjat M, Wahmann M, Bachli H, Guresir E, Vatter H, Raabe A, et al.
Neuroscience
. 2013 Feb;
238:125-34.
PMID: 23415790
Recombinant human erythropoietin (EPO) has been successfully tested as neuroprotectant in brain injury models. The first large clinical trial with stroke patients, however, revealed negative results. Reasons are manifold and...
3.
Alessandri B, Tretzel J, Heimann A, Kempski O
Acta Neurochir Suppl
. 2012 Feb;
114:373-6.
PMID: 22327726
Acute subdural hemorrhage (ASDH) is a frequent and devastating consequence of traumatic brain injury. Tissue damage develops rapidly and makes treatment even more difficult. Management of increased intracranial pressure (ICP)...
4.
Meissner A, Timaru-Kast R, Heimann A, Hoelper B, Kempski O, Alessandri B
Eur Surg Res
. 2011 Sep;
47(3):141-53.
PMID: 21952222
An acute subdural hematoma (ASDH) induces pathomechanisms which worsen outcome after traumatic brain injury, even after a small hemorrhage. Synergistic effects of a small ASDH on brain damage are poorly...
5.
Tamura K, Alessandri B, Heimann A, Kempski O
Neuroscience
. 2011 Aug;
194:262-71.
PMID: 21839806
Cortical spreading depression (CSD) has been shown to cause secondary cell loss in experimental models of brain injury and in patients, and blocking of CSD is a potential neuroprotective strategy....
6.
Alessandri B, Nishioka T, Heimann A, Bullock R, Kempski O
Brain Res
. 2006 Aug;
1111(1):196-202.
PMID: 16890922
Traumatic brain injury is associated with acute subdural hematoma (ASDH) that worsens outcome. Although early removal of blood can reduce mortality, patients still die or remain disabled after surgery and...
7.
Hoelper B, Alessandri B, Heimann A, Behr R, Kempski O
Acta Neurochir (Wien)
. 2005 May;
147(7):767-74.
PMID: 15889319
Background: Oxygen tension sensors have been used to monitor tissue oxygenation in human brain for several years. The working principals of the most frequently used sensors, the Licox (LX) and...
8.
Heimann A, Takeshima T, Alessandri B, Noppens R, Kempski O
Crit Care Med
. 2003 Oct;
31(10):2495-501.
PMID: 14530757
Objective: To examine the effects of hypertonic/hyperoncotic treatment on physiologic variables and regional cerebral blood flow and to test its neuroprotective efficiency in a model of permanent venous ischemia. Design:...
9.
Rice A, Zsoldos R, Chen T, Wilson M, Alessandri B, Hamm R, et al.
Brain Res
. 2002 Feb;
928(1-2):156-9.
PMID: 11844482
Moderately head injured patients often suffer long term neurological sequelae. There is no therapy for brain trauma and current treatments aim only to minimize secondary damage. These secondary effects are...
10.
Ros J, Pecinska N, Alessandri B, Landolt H, Fillenz M
J Neurosci Res
. 2001 Dec;
66(5):790-4.
PMID: 11746403
Experiments were carried out to test the hypothesis that lactate reduces the neurotoxicity of glutamate in vivo. MAP2 immunohistochemistry was used to measure lesion size, and microdialysis to measure the...