B Ahmed Rasheed
Overview
Explore the profile of B Ahmed Rasheed including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
7909
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Recent Articles
1.
Killela P, Pirozzi C, Healy P, Reitman Z, Lipp E, Rasheed B, et al.
Oncotarget
. 2014 Apr;
5(6):1515-25.
PMID: 24722048
Frequent mutations in isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) and the promoter of telomerase reverse transcriptase (TERT) represent two significant discoveries in glioma genomics. Understanding the degree to...
2.
Killela P, Pirozzi C, Reitman Z, Jones S, Rasheed B, Lipp E, et al.
Oncotarget
. 2013 Oct;
5(6):1452-7.
PMID: 24140581
Anaplastic astrocytoma WHO grade III (A3) is a lethal brain tumor that often occurs in middle aged patients. Clinically, it is challenging to distinguish A3 from glioblastoma multiforme (GBM) WHO...
3.
Killela P, Reitman Z, Jiao Y, Bettegowda C, Agrawal N, Diaz Jr L, et al.
Proc Natl Acad Sci U S A
. 2013 Mar;
110(15):6021-6.
PMID: 23530248
Malignant cells, like all actively growing cells, must maintain their telomeres, but genetic mechanisms responsible for telomere maintenance in tumors have only recently been discovered. In particular, mutations of the...
4.
Jin G, Reitman Z, Duncan C, Spasojevic I, Gooden D, Rasheed B, et al.
Cancer Res
. 2012 Dec;
73(2):496-501.
PMID: 23204232
Point mutations at Arg132 of the cytoplasmic NADP(+)-dependent isocitrate dehydrogenase 1 (IDH1) occur frequently in gliomas and result in a gain of function to produce the "oncometabolite" D-2-hydroxyglutarate (D-2HG). The...
5.
Heaphy C, de Wilde R, Jiao Y, Klein A, Edil B, Shi C, et al.
Science
. 2011 Jul;
333(6041):425.
PMID: 21719641
The proteins encoded by ATRX and DAXX participate in chromatin remodeling at telomeres and other genomic sites. Because inactivating mutations of these genes are common in human pancreatic neuroendocrine tumors...
6.
Parsons D, Li M, Zhang X, Jones S, Leary R, Cheng-Ho Lin J, et al.
Science
. 2010 Dec;
331(6016):435-9.
PMID: 21163964
Medulloblastoma (MB) is the most common malignant brain tumor of children. To identify the genetic alterations in this tumor type, we searched for copy number alterations using high-density microarrays and...
7.
Yan H, Parsons D, Jin G, McLendon R, Rasheed B, Yuan W, et al.
N Engl J Med
. 2009 Feb;
360(8):765-73.
PMID: 19228619
Background: A recent genomewide mutational analysis of glioblastomas (World Health Organization [WHO] grade IV glioma) revealed somatic mutations of the isocitrate dehydrogenase 1 gene (IDH1) in a fraction of such...
8.
Parsons D, Jones S, Zhang X, Cheng-Ho Lin J, Leary R, Angenendt P, et al.
Science
. 2008 Sep;
321(5897):1807-12.
PMID: 18772396
Glioblastoma multiforme (GBM) is the most common and lethal type of brain cancer. To identify the genetic alterations in GBMs, we sequenced 20,661 protein coding genes, determined the presence of...