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Ayub Darji

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Articles 37
Citations 464
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Recent Articles
1.
Falcon A, Martinez-Pulgarin S, Lopez-Serrano S, Reytor E, Cid M, Nunez M, et al.
Viruses . 2024 Jun; 16(6). PMID: 38932122
In this study, we pioneered an alternative technology for manufacturing subunit influenza hemagglutinin (HA)-based vaccines. This innovative method involves harnessing the pupae of the Lepidoptera () as natural biofactories in...
2.
Perovic V, Stevanovic K, Bukreyeva N, Paessler S, Maruyama J, Lopez-Serrano S, et al.
Int J Mol Sci . 2024 May; 25(9). PMID: 38732151
The influenza A virus nonstructural protein 1 (NS1), which is crucial for viral replication and immune evasion, has been identified as a significant drug target with substantial potential to contribute...
3.
Lopez-Valinas A, Valle M, Perez M, Darji A, Chiapponi C, Ganges L, et al.
Front Cell Infect Microbiol . 2023 Oct; 13:1258321. PMID: 37780850
Influenza A viruses (IAVs) are characterized by having a segmented genome, low proofreading polymerases, and a wide host range. Consequently, IAVs are constantly evolving in nature causing a threat to...
4.
Lopez-Valinas A, Valle M, Wang M, Darji A, Cantero G, Chiapponi C, et al.
Front Cell Infect Microbiol . 2023 Mar; 13:1111143. PMID: 36992684
Influenza A viruses (IAVs) can infect a wide variety of bird and mammal species. Their genome is characterized by 8 RNA single stranded segments. The low proofreading activity of their...
5.
Lopez-Valinas A, Baioni L, Cordoba L, Darji A, Chiapponi C, Segales J, et al.
Viruses . 2022 Sep; 14(9). PMID: 36146814
Swine influenza viruses (SIV) produce a highly contagious and worldwide distributed disease that can cause important economic losses to the pig industry. Currently, this virus is endemic in farms and,...
6.
Lopez-Valinas A, Sistere-Oro M, Lopez-Serrano S, Baioni L, Darji A, Chiapponi C, et al.
Viruses . 2021 Oct; 13(10). PMID: 34696517
Influenza viruses represent a continuous threat to both animal and human health. The 2009 H1N1 A influenza pandemic highlighted the importance of a swine host in the adaptation of influenza...
7.
Lopez-Serrano S, Cordoba L, Perez-Maillo M, Pleguezuelos P, Remarque E, Ebensen T, et al.
Vaccines (Basel) . 2021 Aug; 9(7). PMID: 34358167
This study aimed to evaluate the immune response and protection correlates against influenza virus (IV) infection in pigs vaccinated with the novel NG34 HA1 vaccine candidate adjuvanted with either CAF01...
8.
Lopez-Serrano S, Neila-Ibanez C, Costa-Hurtado M, Mahmmod Y, Martinez-Martinez J, Galindo-Cardiel I, et al.
Vaccines (Basel) . 2021 Jun; 9(5). PMID: 34065547
, an early colonizer of the nasal cavity in piglets, is a highly heterogeneous species, comprising both commensal and virulent strains. Virulent strains can cause fibrinous polyserositis called Glässer's disease....
9.
Sistere-Oro M, Pedersen G, Cordoba L, Lopez-Serrano S, Christensen D, Darji A
Vet Res . 2020 Apr; 51(1):57. PMID: 32312317
Conserved epitopes are targets commonly researched to be part of universal vaccine candidates against influenza viruses (IV). These conserved epitopes need to be cross-protecting against distinct IV subtypes and to...
10.
Sistere-Oro M, Martinez-Pulgarin S, Solanes D, Veljkovic V, Lopez-Serrano S, Cordoba L, et al.
Vaccine . 2019 Nov; 38(3):416-422. PMID: 31735501
The immunization of poultry where H5 and H7 influenza viruses (IVs) are endemic is one of the strategies to prevent unexpected zoonoses. Our group has been focused on conserved HA-epitopes...