Ayman M Arafat
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Explore the profile of Ayman M Arafat including associated specialties, affiliations and a list of published articles.
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36
Citations
977
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Recent Articles
1.
Meyer N, Kabisch S, Dambeck U, Honsek C, Kemper M, Gerbracht C, et al.
Int J Mol Sci
. 2024 Jun;
25(12).
PMID: 38928106
Lifestyle interventions can prevent type 2 diabetes (T2DM). However, some individuals do not experience anticipated improvements despite weight loss. Biomarkers to identify such individuals at early stages are lacking. Insulin-like...
2.
Kabisch S, Meyer N, Honsek C, Kemper M, Gerbracht C, Arafat A, et al.
Nutrients
. 2022 Nov;
14(22).
PMID: 36432409
Background: T2DM heterogeneity affects responsiveness to lifestyle treatment. Beta-cell failure and nonalcoholic fatty liver disease (NAFLD) independently predict T2DM, but NAFLD inconsistently predicts metabolic response to lifestyle intervention. Aim: We...
3.
Meyer N, Kabisch S, Dambeck U, Honsek C, Kemper M, Gerbracht C, et al.
Eur J Endocrinol
. 2022 Aug;
187(4):555-565.
PMID: 36005859
Objectives: Some individuals develop type 2 diabetes mellitus (T2DM) despite significant metabolic improvements through lifestyle intervention. We tested the hypotheses that insulin growth factor 1 (IGF1) and its binding proteins...
4.
Kabisch S, Honsek C, Kemper M, Gerbracht C, Arafat A, Birkenfeld A, et al.
Acta Diabetol
. 2021 Jul;
58(12):1649-1658.
PMID: 34254189
Aims: As the first long-term RCT on insoluble cereal fibre, the optimal fibre trial demonstrated glycometabolic benefits, confirming cohort studies. The combined study intervention of lifestyle recommendations and supplementation with...
5.
Kabisch S, Honsek C, Kemper M, Gerbracht C, Meyer N, Arafat A, et al.
Mol Nutr Food Res
. 2021 Apr;
65(12):e2000991.
PMID: 33909947
Scope: The Optimal Fibre Trial (OptiFiT) investigates metabolic effects of insoluble cereal fibre in subjects with impaired glucose tolerance (IGT), showing moderate glycemic and anti-inflammatory benefits, especially in subjects with...
6.
Kabisch S, Meyer N, Honsek C, Gerbracht C, Dambeck U, Kemper M, et al.
Nutrients
. 2019 Nov;
11(11).
PMID: 31717901
Background: OptiFiT demonstrated the beneficial effect of insoluble oat fibres on dysglycemia in prediabetes. Recent analyses of OptiFiT and other randomised controlled trials (RCTs) indicated that this effect might be...
7.
Kabisch S, Meyer N, Honsek C, Gerbracht C, Dambeck U, Kemper M, et al.
Nutrients
. 2019 Oct;
11(10).
PMID: 31590438
Background: High intake of cereal fibre is associated with reduced risk for type 2 diabetes and long-term complications. Within the first long-term randomized controlled trial specifically targeting cereal fibre, the...
8.
Mahmoud A, Jones A, Sidgwick G, Arafat A, Alexander Y, Wilkinson F
Cell Physiol Biochem
. 2019 Jul;
53(2):323-336.
PMID: 31359737
Background/aims: Vascular calcification represents a huge clinical problem contributing to adverse cardiovascular events, with no effective treatment currently available. Upregulation of hepatocyte growth factor has been linked with vascular calcification,...
9.
Weickert M, Hattersley J, Kyrou I, Arafat A, Rudovich N, Roden M, et al.
Nutr Diabetes
. 2018 Mar;
8(1):11.
PMID: 29549243
Bile acids (BA) are potent metabolic regulators influenced by diet. We studied effects of isoenergetic increases in the dietary protein and cereal-fiber contents on circulating BA and insulin resistance (IR)...
10.
Honsek C, Kabisch S, Kemper M, Gerbracht C, Arafat A, Birkenfeld A, et al.
Diabetologia
. 2018 Mar;
61(6):1295-1305.
PMID: 29492637
Aims/hypothesis: Insoluble cereal fibres have been shown in large prospective cohort studies to be highly effective in preventing type 2 diabetes, but there is a lack of interventional data. Our...