Ayman El-Guindy
Overview
Explore the profile of Ayman El-Guindy including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
19
Citations
499
Followers
0
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Recent Articles
11.
El-Guindy A, Ghiassi-Nejad M, Golden S, Delecluse H, Miller G
J Virol
. 2012 Oct;
87(1):208-23.
PMID: 23077295
Two transcription factors, ZEBRA and Rta, switch Epstein-Barr virus (EBV) from the latent to the lytic state. While ZEBRA also plays an obligatory role as an activator of replication, it...
12.
El-Guindy A, Heston L, Miller G
PLoS Pathog
. 2010 Sep;
6(8):e1001054.
PMID: 20808903
ZEBRA is a site-specific DNA binding protein that functions as a transcriptional activator and as an origin binding protein. Both activities require that ZEBRA recognizes DNA motifs that are scattered...
13.
Daigle D, Megyola C, El-Guindy A, Gradoville L, Tuck D, Miller G, et al.
J Virol
. 2009 Nov;
84(2):993-1004.
PMID: 19889776
A fundamental problem in studying the latent-to-lytic switch of Epstein-Barr virus (EBV) and the viral lytic cycle itself is the lack of a culture system fully permissive to lytic cycle...
14.
Miller G, El-Guindy A, Countryman J, Ye J, Gradoville L
Adv Cancer Res
. 2007 Apr;
97:81-109.
PMID: 17419942
The seminal experiments of George and Eva Klein helped to define the two life cycles of Epstein-Barr Virus (EBV), namely latency and lytic or productive infection. Their laboratories described latent...
15.
Bhaduri-McIntosh S, Landry M, Nikiforow S, Rotenberg M, El-Guindy A, Miller G
J Infect Dis
. 2007 Jan;
195(4):483-92.
PMID: 17230407
Primary Epstein-Barr virus (EBV) infection is characterized by the presence of IgM antibodies to viral capsid antigen and the absence of antibodies to EB nuclear antigen. Here, using a flow...
16.
El-Guindy A, Heston L, Delecluse H, Miller G
J Virol
. 2007 Jan;
81(7):3303-16.
PMID: 17215287
The Epstein-Barr virus ZEBRA protein controls the viral lytic cycle. ZEBRA activates the transcription of viral genes required for replication. ZEBRA also binds to oriLyt and interacts with components of...
17.
Heston L, El-Guindy A, Countryman J, Dela Cruz C, Delecluse H, Miller G
J Virol
. 2006 Aug;
80(18):9115-33.
PMID: 16940523
The ZEBRA protein of Epstein-Barr virus (EBV) drives the viral lytic cycle cascade. The capacity of ZEBRA to recognize specific DNA sequences resides in amino acids 178 to 194, a...
18.
Miller Jr I, El-Guindy A
J Natl Cancer Inst
. 2002 Dec;
94(23):1733-5.
PMID: 12464640
No abstract available.
19.
Gradoville L, Kwa D, El-Guindy A, Miller G
J Virol
. 2002 May;
76(11):5612-26.
PMID: 11991990
The protein kinase C (PKC) pathway has been considered to be essential for activation of latent Epstein-Barr virus (EBV) into the lytic cycle. The phorbol ester tetradecanoyl phorbol acetate (TPA),...