Ayla Ergun
Overview
Explore the profile of Ayla Ergun including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
23
Citations
1474
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0
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Recent Articles
1.
Patrick E, Taga M, Ergun A, Ng B, Casazza W, Cimpean M, et al.
PLoS Comput Biol
. 2020 Aug;
16(8):e1008120.
PMID: 32804935
Complexity of cell-type composition has created much skepticism surrounding the interpretation of bulk tissue transcriptomic studies. Recent studies have shown that deconvolution algorithms can be applied to computationally estimate cell-type...
2.
Wan Y, Al-Ouran R, Mangleburg C, Perumal T, Lee T, Allison K, et al.
Cell Rep
. 2020 Jul;
32(2):107908.
PMID: 32668255
We present a consensus atlas of the human brain transcriptome in Alzheimer's disease (AD), based on meta-analysis of differential gene expression in 2,114 postmortem samples. We discover 30 brain coexpression...
3.
Crotti A, Sait H, McAvoy K, Estrada K, Ergun A, Szak S, et al.
Sci Rep
. 2019 Jul;
9(1):9477.
PMID: 31263146
Despite Bridging INtegrator 1 (BIN1) being the second most statistically-significant locus associated to Late Onset Alzheimer's Disease, its role in disease pathogenesis remains to be clarified. As reports suggest a...
4.
Magnuson A, Kiner E, Ergun A, Park J, Asinovski N, Ortiz-Lopez A, et al.
Proc Natl Acad Sci U S A
. 2018 Oct;
115(45):E10672-E10681.
PMID: 30348759
FoxP3 T regulatory (Treg) cells are central elements of immunologic tolerance. They are abundant in many tumors, where they restrict potentially favorable antitumor responses. We used a three-pronged strategy to...
5.
Sarma K, Cifuentes-Rojas C, Ergun A, Del Rosario A, Jeon Y, White F, et al.
Cell
. 2017 Sep;
159(5):1228.
PMID: 28898627
No abstract available.
6.
Johnson B, Ren S, Karaca G, Gomez I, Fligny C, Smith B, et al.
J Am Soc Nephrol
. 2017 Jan;
28(6):1769-1782.
PMID: 28130402
Connective tissue growth factor (CTGF), a matrix-associated protein with four distinct cytokine binding domains, has roles in vasculogenesis, wound healing responses, and fibrogenesis and is upregulated in fibroblasts and myofibroblasts...
7.
Ray M, Wiskow O, King M, Ismail N, Ergun A, Wang Y, et al.
J Biol Chem
. 2016 Jul;
291(37):19558-72.
PMID: 27405765
The essential functions of polycomb repressive complex 1 (PRC1) in development and gene silencing are thought to involve long non-coding RNAs (lncRNAs), but few specific lncRNAs that guide PRC1 activity...
8.
Mingueneau M, Boudaoud S, Haskett S, Reynolds T, Nocturne G, Norton E, et al.
J Allergy Clin Immunol
. 2016 Apr;
137(6):1809-1821.e12.
PMID: 27045581
Background: Mass cytometry has recently emerged as a promising tool for clinical research. However, few studies have demonstrated its benefit for patient stratification and biomarker identification. Primary Sjögren's syndrome (pSS)...
9.
Wani A, Boettiger A, Schorderet P, Ergun A, Munger C, Sadreyev R, et al.
Nat Commun
. 2016 Jan;
7:10291.
PMID: 26759081
The genomes of metazoa are organized at multiple scales. Many proteins that regulate genome architecture, including Polycomb group (PcG) proteins, form subnuclear structures. Deciphering mechanistic links between protein organization and...
10.
Banerjee D, Zhao L, Wu L, Palanichamy A, Ergun A, Peng L, et al.
Immunology
. 2015 Dec;
147(4):399-413.
PMID: 26694902
Retinoic acid receptor-related orphan nuclear receptor γ (RORγ) orchestrates a pro-inflammatory gene expression programme in multiple lymphocyte lineages including T helper type 17 (Th17) cells, γδ T cells, innate lymphoid...