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Ayan Mohamud Yusuf

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Articles 19
Citations 212
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Recent Articles
1.
Hermann D, Wang C, Mohamud Yusuf A, Herz J, Doeppner T, Giebel B
J Cereb Blood Flow Metab . 2025 Mar; :271678X251325039. PMID: 40072028
Extracellular vesicles (EVs) convey complex signals between cells that can be used to promote neuronal plasticity and neurological recovery in brain disease models. These EV signals are multimodal and context-dependent,...
2.
Mohamud Yusuf A, Zhang X, Gulbins E, Peng Y, Hagemann N, Hermann D
Neurobiol Dis . 2024 Sep; 201:106682. PMID: 39332507
Sphingolipids comprise a class of lipids, which are composed of a sphingoid base backbone and are essential structural components of cell membranes. Beyond their role in maintaining cellular integrity, several...
3.
Llovera G, Langhauser F, Isla Cainzos S, Hoppen M, Abberger H, Mohamud Yusuf A, et al.
Stroke . 2024 Sep; 55(10):2522-2527. PMID: 39315830
Background: The discrepancy between experimental research and clinical trial outcomes is a persistent challenge in preclinical studies, particularly in stroke research. A possible factor contributing to this issue is the...
4.
Mohamud Yusuf A, Borbor M, Hussner T, Weghs C, Kaltwasser B, Pillath-Eilers M, et al.
Cell Death Dis . 2024 Sep; 15(9):650. PMID: 39231943
Acid sphingomyelinase (ASM) inhibitors are widely used for the treatment of post-stroke depression. They promote neurological recovery in animal stroke models via neurorestorative effects. In a previous study, we found...
5.
Tuz A, Ghosh S, Karsch L, Ttoouli D, Sata S, Ulusoy O, et al.
Nat Cardiovasc Res . 2024 Aug; 3(5):525-540. PMID: 39195931
Post-injury dysfunction of humoral immunity accounts for infections and poor outcomes in cardiovascular diseases. Among immunoglobulins (Ig), IgA, the most abundant mucosal antibody, is produced by plasma B cells in...
6.
Hagemann N, Qi Y, Mohamud Yusuf A, Li A, Zhang X, Spangenberg P, et al.
J Cereb Blood Flow Metab . 2024 Aug; 45(1):171-186. PMID: 39113408
Evaluation of microvascular networks was impeded until recently by the need of histological tissue sectioning, which precluded 3D analyses. Using light-sheet microscopy, we investigated microvascular network characteristics in the peri-infarct...
7.
Hagemann N, Qi Y, Mohamud Yusuf A, Li A, Squire A, Tertel T, et al.
Arterioscler Thromb Vasc Biol . 2024 Feb; 44(4):915-929. PMID: 38357819
Background: Until now, the analysis of microvascular networks in the reperfused ischemic brain has been limited due to tissue transparency challenges. Methods: Using light sheet microscopy, we assessed microvascular network...
8.
Yin D, Wang C, Qi Y, Wang Y, Hagemann N, Mohamud Yusuf A, et al.
J Neuroinflammation . 2023 Sep; 20(1):210. PMID: 37715288
Background: The intravenous delivery of adult neural precursor cells (NPC) has shown promising results in enabling cerebroprotection, brain tissue remodeling, and neurological recovery in young, healthy stroke mice. However, the...
9.
Spangenberg P, Hagemann N, Squire A, Forster N, Krauss S, Qi Y, et al.
Cell Rep Methods . 2023 Apr; 3(3):100436. PMID: 37056368
Light-sheet fluorescence microscopy (LSFM) can produce high-resolution tomograms of tissue vasculature with high accuracy. However, data processing and analysis is laborious due to the size of the datasets. Here, we...
10.
Mohamud Yusuf A, Hagemann N, Zhang X, Zafar M, Hussner T, Bromkamp C, et al.
Basic Res Cardiol . 2022 Aug; 117(1):43. PMID: 36038749
Antidepressants have been reported to enhance stroke recovery independent of the presence of depressive symptoms. They have recently been proposed to exert their mood-stabilizing actions by inhibition of acid sphingomyelinase...