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Aya Mikdache

Explore the profile of Aya Mikdache including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 19
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Recent Articles
1.
El-Hage O, Mikdache A, Boueid M, Degerny C, Tawk M
Cells Dev . 2025 Jan; 181:203993. PMID: 39755275
The temporal control of mitotic exit of individual Schwann cells (SCs) is essential for radial sorting and peripheral myelination. However, it remains unknown when, during their multiple rounds of division,...
2.
Elsaid R, Mikdache A, Diabangouaya P, Gros G, Hernandez P
iScience . 2024 Aug; 27(8):110476. PMID: 39129833
The cyclic recombinase (Cre)/ recombination system is a powerful technique for cell labeling and tracking. However, achieving high spatiotemporal precision in cell tracking using this system is challenging due to...
3.
Elsaid R, Mikdache A, Castillo K, Salloum Y, Diabangouaya P, Gros G, et al.
iScience . 2024 Feb; 27(2):108922. PMID: 38327794
In all organisms studied, from flies to humans, blood cells emerge in several sequential waves and from distinct hematopoietic origins. However, the relative contribution of these ontogenetically distinct hematopoietic waves...
4.
Boueid M, Mikdache A, Lesport E, Delespierre B, Loisel-Duwattez J, Degerny C, et al.
Dev Dyn . 2022 Oct; 252(1):145-155. PMID: 36284447
Background: Schwann cells (SCs) are specialized glial cells of the peripheral nervous system that produce myelin and promote fast action potential propagation. In order to myelinate, SCs engage in a...
5.
Mikdache A, Boueid M, Lesport E, Delespierre B, Loisel-Duwattez J, Degerny C, et al.
Development . 2022 Aug; 149(17). PMID: 35938454
Schwann cells (SCs) migrate along peripheral axons and divide intensively to generate the right number of cells prior to axonal ensheathment; however, little is known regarding the temporal and molecular...
6.
Mikdache A, Boueid M, van der Spek L, Lesport E, Delespierre B, Loisel-Duwattez J, et al.
Sci Rep . 2021 Jun; 11(1):13338. PMID: 34172795
The Regulator of G protein signaling 4 (Rgs4) is a member of the RGS proteins superfamily that modulates the activity of G-protein coupled receptors. It is mainly expressed in the...
7.
Boueid M, Mikdache A, Lesport E, Degerny C, Tawk M
Cells . 2020 Dec; 9(12). PMID: 33302361
Cells encounter countless external cues and the specificity of their responses is translated through a myriad of tightly regulated intracellular signals. For this, Rho GTPases play a central role and...
8.
Mikdache A, Fontenas L, Albadri S, Revenu C, Loisel-Duwattez J, Lesport E, et al.
Cell Mol Life Sci . 2019 Jun; 77(1):161-177. PMID: 31161284
Peripheral nervous system development involves a tight coordination of neuronal birth and death and a substantial remodelling of the myelinating glia cytoskeleton to achieve myelin wrapping of its projecting axons....