Axel Hartke
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Explore the profile of Axel Hartke including associated specialties, affiliations and a list of published articles.
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78
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1522
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Recent Articles
1.
Boudrioua A, Baetz B, Desmadril S, Goulard C, Groo A, Lombard C, et al.
iScience
. 2025 Mar;
28(3):111922.
PMID: 40034853
Antibiotic resistance is a major threat to human health and new drugs are urgently needed. Ideally, these drugs should have several cellular targets in pathogens, decreasing the risk of resistance...
2.
Combret V, Rince I, Cochelin R, Desriac F, Muller C, Soussan D, et al.
Mol Microbiol
. 2025 Feb;
PMID: 39948710
Two PTS transporters involved in the uptake of cellobiose and short cellooligosaccharides were identified in Enterococcus faecalis. Genes coding for the different EII proteins are found in a locus composed...
3.
Combret V, Rince I, Budin-Verneuil A, Muller C, Deutscher J, Hartke A, et al.
Res Microbiol
. 2023 Nov;
175(4):104169.
PMID: 37977353
Enterococcus faecalis is a Gram-positive clinical pathogen causing severe infections. Its survival during infection depends on its ability to utilize host-derived metabolites, such as protein-deglycosylation products. We have identified in...
4.
Wasselin V, Budin-Verneuil A, Rince I, Leger L, Boukerb A, Hartke A, et al.
Res Microbiol
. 2022 Aug;
173(8):103982.
PMID: 35931249
In this work, the physiological roles of the primary peroxide scavenging activities of Enterococcus faecium AUS0004 strain were analysed. This healthcare-associated pathogen harbours genes encoding putative NADH peroxidase (Npr), alkyl...
5.
Baetz B, Boudrioua A, Hartke A, Giraud C
Antibiotics (Basel)
. 2021 Sep;
10(9).
PMID: 34572698
Gram positive pathogens are a significant cause of healthcare-associated infections, with and being the most prevalent ones. Vancomycin, a last resort glycopeptide, is used to fight these bacteria but the...
6.
Wasselin V, Staerck C, Rince I, Leger L, Budin-Verneuil A, Hartke A, et al.
Res Microbiol
. 2021 Sep;
172(6):103876.
PMID: 34474124
The manganese superoxide dismutase (SodA) of E. faecium strain AUS0004 has been characterised. It is most closely related to Enterococcus hirae, Enterococcus durans, Enterococcus villorium, and Enterococcus mundtii with 100%,...
7.
Coupri D, Verneuil N, Hartke A, Liebaut A, Lequeux T, Pfund E, et al.
J Antimicrob Chemother
. 2021 Aug;
76(11):2778-2786.
PMID: 34450626
Background: MRSA are high-priority multidrug-resistant pathogens. Although there are still some antibiotics active against MRSA, continuous efforts to discover new antibiotics and treatment strategies are needed because resistance to these...
8.
Staerck C, Wasselin V, Budin-Verneuil A, Rince I, Cacaci M, Weigel M, et al.
FEMS Microbiol Lett
. 2021 Apr;
368(8).
PMID: 33864460
Glycerol (Gly) can be dissimilated by two pathways in bacteria. Either this sugar alcohol is first oxidized to dihydroxyacetone (DHA) and then phosphorylated or it is first phosphorylated to glycerol-3-phosphate...
9.
Grand M, Riboulet-Bisson E, Deutscher J, Hartke A, Sauvageot N
Appl Environ Microbiol
. 2020 Jul;
86(18).
PMID: 32680872
Enterococci are Gram-positive bacteria present in the healthy human microbiota, but they are also a leading cause of nosocomial infections. Maltodextrin utilization by has been identified as an important factor...
10.
Boudrioua A, Li Y, Hartke A, Giraud C
FEMS Microbiol Lett
. 2020 Apr;
367(8).
PMID: 32277698
The increasing spread of antibiotic resistant bacteria is a major human health concern. The challenging development of new effective antibiotics has led to focus on seeking synergistic antibiotic combinations. Vancomycin...