Avni Desai
Overview
Explore the profile of Avni Desai including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
788
Followers
0
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Recent Articles
1.
Sethna Z, Guasp P, Reiche C, Milighetti M, Ceglia N, Patterson E, et al.
Nature
. 2025 Feb;
PMID: 39972124
A fundamental challenge for cancer vaccines is to generate long-lived functional T cells that are specific for tumour antigens. Here we find that mRNA-lipoplex vaccines against somatic mutation-derived neoantigens may...
2.
Harrold E, Foote M, Rousseau B, Walch H, Kemel Y, Richards A, et al.
Nat Med
. 2023 Oct;
29(10):2458-2463.
PMID: 37845474
Metastatic and localized mismatch repair-deficient (dMMR) tumors are exquisitely sensitive to immune checkpoint blockade (ICB). The ability of ICB to prevent dMMR malignant or pre-malignant neoplasia development in patients with...
3.
Cytryn S, Moy R, Cowzer D, Shah R, Chou J, Joshi S, et al.
Lancet Oncol
. 2023 Sep;
24(10):1073-1082.
PMID: 37666264
Background: The addition of nivolumab to chemotherapy improves survival in patients with advanced oesophagogastric (oesophageal, gastric, or gastro-oesophageal junction) adenocarcinoma; however, outcomes remain poor. We assessed the safety and activity...
4.
Rojas L, Sethna Z, Soares K, Olcese C, Pang N, Patterson E, et al.
Nature
. 2023 May;
618(7963):144-150.
PMID: 37165196
Pancreatic ductal adenocarcinoma (PDAC) is lethal in 88% of patients, yet harbours mutation-derived T cell neoantigens that are suitable for vaccines . Here in a phase I trial of adjuvant...
5.
Cercek A, Lumish M, Sinopoli J, Weiss J, Shia J, Lamendola-Essel M, et al.
N Engl J Med
. 2022 Jun;
386(25):2363-2376.
PMID: 35660797
Background: Neoadjuvant chemotherapy and radiation followed by surgical resection of the rectum is a standard treatment for locally advanced rectal cancer. A subset of rectal cancer is caused by a...
6.
King K, Key-Hagan M, Desai A, Mundy T, Shittu A, Roberts L, et al.
Am J Mens Health
. 2022 May;
16(3):15579883221097801.
PMID: 35549937
Black men experience higher levels of chronic stress, life stressors, and discrimination due to oppressive social and economic conditions. Black men are at greater risk of depression, but most published...
7.
Machon V, Desai A, Levorova J, Hirjak D, Brizman E, Foltan R
Prague Med Rep
. 2019 Oct;
120(2-3):64-73.
PMID: 31586505
Sub-condylar fractures of the temporomandibular joint can be treated by an extraoral or intraoral approach. Trans-masseteric antero-parotid approach (TMAP) is an extraoral approach utilising a retromandibular incision. The authors evaluated...
8.
Wang T, Lee L, Vyas M, Zhang L, Ganesh K, Firat C, et al.
Mod Pathol
. 2019 Jun;
32(10):1551-1562.
PMID: 31175329
Double somatic mismatch-repair-gene mutation/alteration is a recently recognized molecular mechanism that underlies microsatellite instability-high in some colorectal carcinomas. It remains to be determined whether and how microsatellite instability-high tumors with...
9.
Mondaca S, Margolis M, Sanchez-Vega F, Jonsson P, Riches J, Ku G, et al.
Gastric Cancer
. 2018 Aug;
22(2):355-362.
PMID: 30088161
Background: Trastuzumab with cisplatin and fluoropyrimidine is the standard treatment in metastatic HER2-positive gastric or gastroesophageal (GE) junction adenocarcinoma; however, there is limited data on the efficacy of trastuzumab in...