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Aurore Thomazeau

Explore the profile of Aurore Thomazeau including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 547
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Recent Articles
1.
Barnes S, Thomazeau A, Finnie P, Heinrich M, Heynen A, Komiyama N, et al.
Cell Rep . 2025 Feb; :115311. PMID: 39983718
N-methyl-D-aspartate (NMDA)-induced spine shrinkage proceeds independently of ion flux and requires the initiation of de novo protein synthesis. Using subtype-selective pharmacological and genetic tools, we find that structural plasticity is...
2.
Barnes S, Thomazeau A, Finnie P, Heinrich M, Heynen A, Komiyama N, et al.
bioRxiv . 2025 Jan; PMID: 39764032
It is well known that activation of NMDA receptors can trigger long-term synaptic depression (LTD) and that a morphological correlate of this functional plasticity is spine retraction and elimination. Recent...
3.
Thomazeau A, Lassalle O, Manzoni O
Front Neurosci . 2023 Oct; 17:1171797. PMID: 37841687
Down syndrome (DS), the most prevalent cause of intellectual disability, stems from a chromosomal anomaly resulting in an entire or partial extra copy of chromosome 21. This leads to intellectual...
4.
Hayden D, Finnie P, Thomazeau A, Li A, Cooke S, Bear M
J Neurosci . 2023 Sep; 43(44):7307-7321. PMID: 37714707
In mouse primary visual cortex (V1), familiar stimuli evoke significantly altered responses when compared with novel stimuli. This stimulus-selective response plasticity (SRP) was described originally as an increase in the...
5.
Hayden D, Finnie P, Thomazeau A, Li A, Cooke S, Bear M
bioRxiv . 2023 Feb; PMID: 36747661
Significance Statement: Repeated exposure to stimuli that portend neither reward nor punishment leads to behavioral habituation, enabling organisms to dedicate attention to novel or otherwise significant features of the environment....
6.
Wong H, Rannio S, Jones V, Thomazeau A, Sjostrom P
J Physiol . 2020 Nov; 599(2):367-387. PMID: 33141440
In the textbook view, N-methyl-d-aspartate (NMDA) receptors are postsynaptically located detectors of coincident activity in Hebbian learning. However, controversial presynaptically located NMDA receptors (preNMDARs) have for decades been repeatedly reported...
7.
Thomazeau A, Bosch M, Essayan-Perez S, Barnes S, De Jesus-Cortes H, Bear M
Mol Psychiatry . 2020 Jul; 26(9):4652-4669. PMID: 32606374
Many neurodevelopmental disorders are characterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about how these are related. Previous work in the Fmr1 mouse...
8.
Brock J, Thomazeau A, Watanabe A, Li S, Sjostrom P
Front Synaptic Neurosci . 2020 Apr; 12:11. PMID: 32292337
Long-term synaptic plasticity is widely believed to underlie learning and memory in the brain. Whether plasticity is primarily expressed pre- or postsynaptically has been the subject of considerable debate for...
9.
Bilbao A, Neuhofer D, Sepers M, Wei S, Eisenhardt M, Hertle S, et al.
iScience . 2020 Mar; 23(3):100951. PMID: 32179475
The nucleus accumbens (NAc) plays a key role in drug-related behavior and natural reward learning. Synaptic plasticity in dopamine D1 and D2 receptor medium spiny neurons (MSNs) of the NAc...
10.
Fong M, Finnie P, Kim T, Thomazeau A, Kaplan E, Cooke S, et al.
Cereb Cortex . 2019 Dec; 30(4):2555-2572. PMID: 31832634
Primary visual cortex (V1) is the locus of numerous forms of experience-dependent plasticity. Restricting visual stimulation to one eye at a time has revealed that many such forms of plasticity...